Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 11/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL5055130 | 0.93 | NR4A2 (0.37) | KDM4ENR4A2RORCHTR3APLK1 | |
| SCHEMBL11553625 | 0.68 | NR4A2 (0.69) | KDM4ENR4A2RORCHTR3ATNF | |
| SCHEMBL31601057 | 0.68 | NR4A2 (0.69) | KDM4ENR4A2RORCHTR3ATNF | |
| SCHEMBL20538723 | 0.65 | NR4A2 (0.46) | NR4A2HTR3AALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL12486470 | 0.62 | KDM4E (0.69) | KDM4EHTR3APLK1ALDH1A1GAA | |
| SCHEMBL3678410 | 0.61 | HTR3A (0.51) | KDM4ENR4A2RORCHTR3AALDH1A1 | |
| SCHEMBL15421223 | 0.61 | HTR3A (0.54) | KDM4ENR4A2RORCHTR3ACYP1A2 | |
| SCHEMBL15421267 | 0.60 | NR4A2 (0.56) | KDM4ENR4A2RORCHTR3AAKR1C3 | |
| SCHEMBL15174383 | 0.60 | RORC (0.53) | KDM4ENR4A2RORCALDH1A1CYP2C9 | |
| SCHEMBL9263144 | 0.60 | NR4A2 (0.60) | KDM4ENR4A2RORCALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200155568-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2020-05-21 | — | — | US | disclosed |
| US-10555952-B2 | Pharmaceutical compositions and methods for anesthesiological applications | MELT PHARMACEUTICALS, INC. (US) | 2020-02-11 | — | — | US | disclosed |
| US-20180303847-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10555952-B2 | Pharmaceutical compositions and methods for anesthesiological applications | GRIN2B, GRIN3A, GABRA5 | KDM4E 1945/4885NR4A2 674/4885RORC 257/4885 |
| US-20200155568-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN2B, GRIN3A, GABRA5 | KDM4E 1945/4885NR4A2 674/4885RORC 257/4885 |
| US-20180303847-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN2B, GRIN3A, GABRA5 | KDM4E 1945/4885NR4A2 674/4885RORC 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.