Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 6/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.41 |
| ▸ | HTR3B | O95264 | 5/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.41 |
| ▸ | CHRNG | P07510 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRND | Q07001 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20538722 | 0.65 | KDM4E (0.37) | NR4A2HTR3ACYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL27743671 | 0.64 | HTR3A (0.69) | NR4A2CREBBPHTR3AHTR3EHTR3B | |
| SCHEMBL28068117 | 0.61 | NR4A2 (0.70) | NR4A2CREBBPLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29156595 | 0.61 | NR4A2 (0.70) | NR4A2CREBBPHTR3AHTR3EHTR3B | |
| SCHEMBL1093530 | 0.61 | NR4A2 (1.00) | NR4A2CREBBPMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30031033 | 0.61 | NR4A2 (1.00) | NR4A2CREBBPMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28283182 | 0.61 | NR4A2 (0.70) | NR4A2CREBBPHTR3AHTR3EHTR3B | |
| SCHEMBL6684094 | 0.61 | NR4A2 (0.69) | NR4A2CREBBPHTR3AHTR3EHTR3B | |
| SCHEMBL15175554 | 0.61 | NR4A2 (0.64) | NR4A2CREBBPLMNAHRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28254334 | 0.60 | NR4A2 (0.97) | NR4A2CREBBPMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200155568-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2020-05-21 | — | — | US | disclosed |
| US-10555952-B2 | Pharmaceutical compositions and methods for anesthesiological applications | MELT PHARMACEUTICALS, INC. (US) | 2020-02-11 | — | — | US | disclosed |
| US-20180303847-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10555952-B2 | Pharmaceutical compositions and methods for anesthesiological applications | GRIN2B, GRIN3A, GABRA5 | NR4A2 674/4885CREBBP 1115/4885HTR3A 222/4885 |
| US-20200155568-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN2B, GRIN3A, GABRA5 | NR4A2 674/4885CREBBP 1115/4885HTR3A 222/4885 |
| US-20180303847-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS | GRIN2B, GRIN3A, GABRA5 | NR4A2 674/4885CREBBP 1115/4885HTR3A 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.