Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28419750 | 1.00 | FDPS (0.48) | FDPSGGPS1TSHRTHRBSMPD1 | |
| Alcohol SCHEMBL14672676 | 0.95 | FDPS (0.45) | FDPSGGPS1TSHRSMPD1 | |
| SCHEMBL11688845 | 0.91 | LMNA (0.59) | FDPSGGPS1TSHR | |
| SCHEMBL27285703 | 0.84 | FDPS (0.45) | FDPSGGPS1TSHRSMPD1 | |
| SCHEMBL11616812 | 0.83 | FDPS (0.48) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL4457163 | 0.82 | TSHR (0.57) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL11200974 | 0.82 | FDPS (0.52) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL4952751 | 0.81 | FDPS (0.46) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL7115421 | 0.81 | FDPS (0.46) | FDPSGGPS1TSHRTHRBSMPD1 | |
| SCHEMBL11391528 | 0.80 | FDPS (0.50) | FDPSGGPS1TSHRTHRBSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956182-B2 | Process for preparing optically active alcohols | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2011-06-07 | — | — | US | disclosed |
| US-20090062527-A1 | Process for Preparing Optically Active Alcohols | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1988071-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE ALCOHOL | Kotobuki Pharmaceutical Co., Ltd. (JP) | 2008-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062527-A1 | Process for Preparing Optically Active Alcohols | ADH1C, ADH1A, ADH5 | FDPS 1925/4885GGPS1 1753/4885TSHR 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.