Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20511467 | 1.00 | TSHR (0.48) | TSHRRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL2653688 | 0.85 | TSHR (0.53) | TSHRRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL8713659 | 0.81 | TSHR (0.49) | TSHRRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL26688084 | 0.78 | L3MBTL1 (0.51) | TSHRRAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL8179771 | 0.77 | ALDH1A1 (0.51) | TSHRALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL26688063 | 0.76 | TSHR (0.44) | TSHRRAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22640237 | 0.75 | TSHR (0.47) | TSHRRAB9AALDH1A1SMN1; SMN2ATM | |
| SCHEMBL26688060 | 0.75 | ATM (0.45) | TSHRRAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL8188601 | 0.74 | GABRA2 (0.47) | TSHRALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL16625947 | 0.73 | TSHR (0.39) | TSHRALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829792-B2 | Biocatalytic synthesis of strained carbocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-11-10 | — | — | US | disclosed |
| US-10829792-B2 | Biocatalytic synthesis of strained carbocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-11-10 | — | — | US | disclosed |
| US-20180305721-A1 | Biocatalytic Synthesis of Strained Carbocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-10-25 | — | — | US | disclosed |