Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2653688 | 0.84 | TSHR (0.53) | TSHRALDH1A1RAB9AATML3MBTL1 | |
| SCHEMBL8713659 | 0.80 | TSHR (0.49) | TSHRALDH1A1RAB9AATML3MBTL1 | |
| SCHEMBL26688084 | 0.77 | L3MBTL1 (0.51) | TSHRALDH1A1RAB9AATML3MBTL1 | |
| SCHEMBL8179771 | 0.76 | ALDH1A1 (0.51) | TSHRALDH1A1ATML3MBTL1 | |
| SCHEMBL20511467 | 0.75 | TSHR (0.48) | TSHRALDH1A1RAB9AATML3MBTL1 | |
| SCHEMBL20540334 | 0.75 | TSHR (0.48) | TSHRALDH1A1RAB9AATML3MBTL1 | |
| SCHEMBL26688063 | 0.75 | TSHR (0.44) | TSHRALDH1A1RAB9AATML3MBTL1 | |
| SCHEMBL26688060 | 0.73 | ATM (0.45) | TSHRALDH1A1RAB9AATML3MBTL1 | |
| SCHEMBL8188601 | 0.72 | GABRA2 (0.47) | TSHRALDH1A1 | |
| SCHEMBL26688058 | 0.71 | ATM (0.46) | TSHRALDH1A1RAB9AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829792-B2 | Biocatalytic synthesis of strained carbocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-11-10 | — | — | US | disclosed |