Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2653688 | 0.95 | TSHR (0.53) | TSHRLMNARAB9AATML3MBTL1 | |
| SCHEMBL8179771 | 0.85 | ALDH1A1 (0.51) | TSHRLMNAATML3MBTL1ALDH1A1 | |
| SCHEMBL26688084 | 0.83 | L3MBTL1 (0.51) | TSHRLMNARAB9AATML3MBTL1 | |
| SCHEMBL8188601 | 0.82 | GABRA2 (0.47) | TSHRALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL7823315 | 0.81 | LMNA (0.67) | TSHRLMNARAB9AALDH1A1MAPT | |
| SCHEMBL26688063 | 0.81 | TSHR (0.44) | TSHRRAB9AATML3MBTL1ALDH1A1 | |
| SCHEMBL20540334 | 0.81 | TSHR (0.48) | TSHRLMNARAB9AATML3MBTL1 | |
| SCHEMBL20511467 | 0.81 | TSHR (0.48) | TSHRLMNARAB9AATML3MBTL1 | |
| SCHEMBL26688060 | 0.80 | ATM (0.45) | TSHRRAB9AATML3MBTL1ALDH1A1 | |
| SCHEMBL22640237 | 0.80 | TSHR (0.47) | TSHRRAB9AATML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998003491-A1 | DIPHENYL-CYCLOPROPENES AS SELECTIVE K-AGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-01-29 | — | — | WO | disclosed |