Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030047 | 0.86 | RAB9A (0.64) | TSHRAPEX1PDK1PDK2PDK3 | |
| SCHEMBL7254129 | 0.84 | KCNMA1 (0.58) | MEN1KMT2APOLBTSHRMAPT | |
| SCHEMBL11554796 | 0.81 | MEN1 (0.51) | MEN1KMT2APOLBEPHX1PDK1 | |
| SCHEMBL11135310 | 0.81 | TSHR (0.56) | POLBTSHRAPEX1MAPTNPC1 | |
| SCHEMBL11801105 | 0.81 | MAPK1 (0.56) | MEN1KMT2APOLBTSHRAPEX1 | |
| SCHEMBL9819465 | 0.80 | MAPT (0.59) | MEN1KMT2APOLBEPHX1PDK1 | |
| SCHEMBL2388970 | 0.79 | EPHX1 (0.70) | MEN1KMT2APOLBEPHX1PDK1 | |
| SCHEMBL1016535 | 0.79 | TSHR (0.54) | TSHRAPEX1MAPTNPC1RAB9A | |
| SCHEMBL10706727 | 0.79 | TSHR (0.50) | MEN1KMT2APOLBTSHRAPEX1 | |
| SCHEMBL10810548 | 0.79 | TSHR (0.50) | MEN1KMT2APOLBTSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180305231-A1 | COMPOSITE, A METHOD OF MAKING THEREOF, AND A METHOD FOR DEGRADING A POLLUTANT | KING ABDULAZIZ UNIVERSITY (SA) | 2018-10-25 | — | — | US | disclosed |