Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.55 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168398 | 0.82 | TLR8 (0.69) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL2514453 | 0.82 | TLR8 (0.56) | TLR8MBNL1KCNH2ALDH1A1GLA | |
| SCHEMBL17713567 | 0.81 | TLR8 (0.63) | TLR8 | |
| SCHEMBL28278237 | 0.81 | TLR8 (0.55) | TLR8KCNH2ALDH1A1GLAMAPT | |
| SCHEMBL27870558 | 0.81 | TLR8 (0.68) | TLR8KCNH2ALDH1A1GLAMAPT | |
| SCHEMBL2054396 | 0.81 | TLR8 (0.55) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL28793625 | 0.81 | TLR8 (0.68) | TLR8KCNH2ALDH1A1GLAMAPT | |
| SCHEMBL14360658 | 0.80 | ALDH1A1 (0.45) | TLR8MBNL1ALDH1A1GLAMAPT | |
| SCHEMBL28743898 | 0.79 | TLR8 (0.61) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL287399 | 0.79 | TLR8 (0.61) | TLR8ALDH1A1GLAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334087-B1 | ANTIMICROBIAL FOR IN-VITRO DIAGNOSTIC KITS | ABBOTT LABORATORIES (US) | 1992-09-23 | — | — | EP | claimed |
| US-4931446-A | Antimicrobial for in-vitro diagnostic kits | ABBOTT LABORATORIES (US) | 1990-06-05 | — | — | US | claimed |
| EP-0334087-A1 | Antimicrobial for in-vitro diagnostic kits | ABBOTT LABORATORIES (US) | 1989-09-27 | — | — | EP | claimed |
| EP-0334087-B1 | ANTIMICROBIAL FOR IN-VITRO DIAGNOSTIC KITS | ABBOTT LABORATORIES (US) | 1992-09-23 | — | — | EP | disclosed |
| US-4931446-A | Antimicrobial for in-vitro diagnostic kits | ABBOTT LABORATORIES (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0334087-A1 | Antimicrobial for in-vitro diagnostic kits | ABBOTT LABORATORIES (US) | 1989-09-27 | — | — | EP | disclosed |