Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547285 | 0.89 | KCNH2 (0.56) | CYP3A4GRM5CYP1A2KCNH2KMT2A | |
| SCHEMBL20547288 | 0.89 | LMNA (0.50) | CYP3A4GRM5KCNH2KMT2AALDH1A1 | |
| SCHEMBL20547218 | 0.89 | KMT2A (0.51) | KMT2AALDH1A1LMNAMAPTTSHR | |
| SCHEMBL20546709 | 0.86 | LMNA (0.51) | CYP1A2KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL20547217 | 0.82 | LMNA (0.47) | CYP3A4CYP1A2KCNH2KMT2ALMNA | |
| SCHEMBL20547362 | 0.82 | SMN1; SMN2 (0.53) | CYP3A4CYP1A2KCNH2KMT2AALDH1A1 | |
| SCHEMBL20547293 | 0.80 | NPC1 (0.54) | KMT2AALDH1A1LMNAMAPTTSHR | |
| SCHEMBL20547245 | 0.78 | NPC1 (0.53) | CYP3A4CYP1A2KCNH2KMT2AALDH1A1 | |
| SCHEMBL20547246 | 0.78 | NPC1 (0.53) | KMT2AALDH1A1LMNAMAPTTSHR | |
| SCHEMBL5958562 | 0.72 | KMT2A (0.58) | DPP4CYP1A2KCNH2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3560927-B1 | AZEPINE DERIVATIVES ACTING AS 5-HT7 RECEPTOR MODULATORS | KOREA INST SCI & TECH (KR) | 2023-04-19 | — | — | EP | disclosed |
| EP-3560927-A1 | AZEPINE DERIVATIVE ACTING AS 5-HT7 RECEPTOR MODULATOR | Korea Institute of Science and Technology (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-10435408-B2 | Azepine derivatives as 5-HT7 receptor modulators | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-10-08 | — | — | US | disclosed |
| US-20180312509-A1 | AZEPINE DERIVATIVES AS 5-HT7 RECEPTOR MODULATORS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2018-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312509-A1 | AZEPINE DERIVATIVES AS 5-HT7 RECEPTOR MODULATORS | HTR7, HTR5A, HTR3A | DPP4 1581/4885CYP3A4 800/4885GRM5 31/4885 |
| US-10435408-B2 | Azepine derivatives as 5-HT7 receptor modulators | HTR7, HTR5A, HTR3A | DPP4 1581/4885CYP3A4 800/4885GRM5 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.