Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337645 | 0.82 | LPL (0.42) | GPR84PRMT5WDR77HTR2AHTR1A | |
| SCHEMBL1337282 | 0.73 | LPL (0.50) | HTR2AHTR1A | |
| SCHEMBL15912503 | 0.73 | LPL (0.42) | GPR84PRMT5WDR77HTR2A | |
| SCHEMBL15897087 | 0.70 | ALDH1A1 (0.56) | PRMT5WDR77MTNR1AMTNR1BHTR1A | |
| SCHEMBL758451 | 0.70 | CYP2D6 (0.49) | HTR2AMTNR1AMTNR1BSLC6A4HTR1A | |
| SCHEMBL1335521 | 0.69 | GPR84 (0.73) | GPR84HTR2ATRPM8MTNR1AMTNR1B | |
| SCHEMBL25776268 | 0.69 | LPL (0.37) | GPR84PRMT5WDR77HTR1A | |
| Alcohol SCHEMBL27855752 | 0.68 | TGM2 (0.80) | TGM2CES1AGTR1CCNB2CDK1 | |
| SCHEMBL12016746 | 0.68 | HTR1A (0.56) | HTR2AMTNR1AMTNR1BSLC6A4HTR1A | |
| SCHEMBL136581 | 0.68 | TGM2 (1.00) | TGM2CES1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566847-B1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | ICOZEN THERAPEUTICS PVT LTD (IN) | 2018-11-07 | — | — | EP | disclosed |