Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.37 |
| ▸ | ITGAL | P20701 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21870781 | 1.00 | GPR84 (0.42) | GPR84ITGB2ICAM1ITGALMAPT | |
| SCHEMBL22603078 | 1.00 | GPR84 (0.42) | GPR84ITGB2ICAM1ITGALMAPT | |
| SCHEMBL20555924 | 0.90 | GPR84 (0.41) | GPR84ITGB2ICAM1ITGALMAPT | |
| SCHEMBL21870780 | 0.90 | GPR84 (0.41) | GPR84ITGB2ICAM1ITGALMAPT | |
| SCHEMBL20555822 | 0.86 | HTR2A (0.42) | GPR84ITGB2ICAM1ITGALMAPT | |
| SCHEMBL21870765 | 0.86 | HTR2A (0.42) | GPR84ITGB2ICAM1ITGALMAPT | |
| SCHEMBL22603075 | 0.86 | HTR2A (0.42) | GPR84ITGB2ICAM1ITGALMAPT | |
| SCHEMBL20555820 | 0.83 | GPR84 (0.42) | GPR84ITGB2ICAM1ITGALMAPT | |
| SCHEMBL21870777 | 0.83 | GPR84 (0.42) | GPR84ITGB2ICAM1ITGALMAPT | |
| SCHEMBL21870764 | 0.80 | GPR84 (0.59) | GPR84MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2024-07-02 | — | — | US | disclosed |
| US-20200340024-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-10-29 | — | — | US | disclosed |
| US-10612056-B2 | Beta-substituted non-canonical amino acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-04-07 | — | — | US | disclosed |
| US-20180327793-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024731-B2 | Methods and enzyme catalysts for the synthesis of non-canonical amino acids | AANAT, AADAT, TPH1 | GPR84 3894/4885ITGB2 4807/4885ICAM1 4847/4885 |
| US-20200340024-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | AANAT, AADAT, TPH1 | GPR84 3894/4885ITGB2 4807/4885ICAM1 4847/4885 |
| US-10612056-B2 | Beta-substituted non-canonical amino acids | AANAT, TPH1, AADAT | GPR84 3415/4885ITGB2 4297/4885ICAM1 4746/4885 |
| US-20180327793-A1 | METHODS AND ENZYME CATALYSTS FOR THE SYNTHESIS OF NON-CANONICAL AMINO ACIDS | AANAT, AADAT, TPH1 | GPR84 3894/4885ITGB2 4807/4885ICAM1 4847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.