Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587951 | 0.85 | BTK (0.40) | DRD2HTR1DDRD3 | |
| SCHEMBL16843297 | 0.84 | DRD2 (0.38) | DRD2HTR1DDRD3 | |
| SCHEMBL10280563 | 0.83 | DRD2 (0.37) | DRD2HTR1DDRD3 | |
| SCHEMBL13354535 | 0.82 | DRD2 (0.33) | DRD2HTR1DDRD3 | |
| SCHEMBL2481313 | 0.80 | KDM4E (0.43) | — | |
| SCHEMBL16783722 | 0.80 | ALDH1A1 (0.50) | — | |
| SCHEMBL12174857 | 0.80 | MAPT (0.34) | DRD2HTR1DDRD3CXCR2 | |
| SCHEMBL5544919 | 0.78 | RORC (0.34) | DRD2HTR1DDRD3CXCR2 | |
| SCHEMBL5544926 | 0.78 | RORC (0.34) | DRD2HTR1DDRD3CXCR2 | |
| SCHEMBL13132554 | 0.77 | DRD2 (0.33) | DRD2HTR1DDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442973-B1 | NOVEL COMPOUNDS AS AUTOTAXIN INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LEGOCHEM BIOSCIENCES INC (KR) | 2022-08-31 | — | — | EP | disclosed |
| EP-3442973-A1 | NOVEL COMPOUNDS AS AUTOTAXIN INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Legochem Bioscience Ltd. (KR) | 2019-02-20 | — | — | EP | disclosed |
| WO-2018212534-A1 | NOVEL COMPOUNDS AS AUTOTAXIN INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LEGOCHEM BIOSCIENCES, INC. (KR) | 2018-11-22 | — | — | WO | disclosed |