Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587951 | 0.83 | BTK (0.40) | DRD2HTR1DDRD3 | |
| SCHEMBL20564634 | 0.82 | DRD2 (0.36) | DRD2HTR1DDRD3 | |
| SCHEMBL16783722 | 0.76 | ALDH1A1 (0.50) | — | |
| SCHEMBL16843297 | 0.75 | DRD2 (0.38) | DRD2HTR1DDRD3 | |
| SCHEMBL10280563 | 0.74 | DRD2 (0.37) | DRD2HTR1DDRD3 | |
| SCHEMBL5801807 | 0.74 | NAAA (0.39) | DRD2HTR1DDRD3 | |
| SCHEMBL13389501 | 0.73 | LMNA (0.37) | DRD2HTR1DDRD3 | |
| SCHEMBL2481313 | 0.72 | KDM4E (0.43) | — | |
| SCHEMBL16333698 | 0.72 | BTK (0.40) | DRD2HTR1DDRD3 | |
| SCHEMBL25608659 | 0.72 | BTK (0.40) | DRD2HTR1DDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058846-A1 | 4,6-DIAMINONICOTINAMIDE COMPOUND | アステラス製薬株式会社 (JP) | 2010-05-27 | — | — | WO | disclosed |