Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.47 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888206 | 0.81 | RARA (0.56) | IKBKBRARAKMT2AMEN1ALDH1A1 | |
| SCHEMBL6033341 | 0.78 | IKBKB (0.49) | IKBKBRARAKMT2AMEN1ALDH1A1 | |
| SCHEMBL22321021 | 0.74 | RARA (0.44) | IKBKBRARAKMT2AMEN1ALDH1A1 | |
| SCHEMBL30746817 | 0.74 | RARA (0.44) | IKBKBRARAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8570459 | 0.74 | RARA (0.55) | IKBKBRARAKMT2AMEN1LMNA | |
| SCHEMBL8572145 | 0.74 | RARA (0.55) | IKBKBRARAKMT2AMEN1LMNA | |
| SCHEMBL7689456 | 0.74 | IKBKB (0.49) | IKBKBRARAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5888286 | 0.73 | RARA (0.64) | IKBKBRARAKMT2AMEN1ALDH1A1 | |
| SCHEMBL20790232 | 0.72 | MAOA (0.42) | KMT2AMEN1ALDH1A1LMNAGPR55 | |
| SCHEMBL20565375 | 0.72 | IKBKB (0.48) | IKBKBRARAKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195424-B2 | Antibiotic compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2025-01-14 | — | — | US | disclosed |
| US-20220095614-A1 | Antibiotic Compounds | THE GENERAL HOSPITAL CORPORATION | 2022-03-31 | — | — | US | disclosed |
| US-11278025-B2 | Antibiotic compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2022-03-22 | — | — | US | disclosed |
| US-20200190009-A1 | Antibiotic Compounds | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-06-18 | — | — | US | disclosed |
| WO-2018213609-A1 | ANTIBIOTIC COMPOUNDS | AUSUBEL FREDERICK M (US) | 2018-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190009-A1 | Antibiotic Compounds | CUTA, NRDC, CLPP | IKBKB 2203/4885RARA 30/4885KMT2A 4368/4885 |
| US-20220095614-A1 | Antibiotic Compounds | CUTA, NRDC, CLPP | IKBKB 2203/4885RARA 30/4885KMT2A 4368/4885 |
| US-12195424-B2 | Antibiotic compounds | CUTA, NRDC, CLPP | IKBKB 2203/4885RARA 30/4885KMT2A 4368/4885 |
| US-11278025-B2 | Antibiotic compounds | CUTA, NRDC, CLPP | IKBKB 2203/4885RARA 30/4885KMT2A 4368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.