SCHEMBL20565449

SCHEMBL20565449

Cc1cc(Oc2ccc(Cl)c(C)c2)ccc1N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.57
MEN1 O00255 3/20 0.57
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.55
NR4A1 P22736 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.45
MCL1 Q07820 1/20 0.45
HTR2A P28223 1/20 0.44
SLC6A4 P31645 1/20 0.44
KCNH2 Q12809 1/20 0.44
ALDH1A1 P00352 5/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CD44 P16070 1/20 0.43
ICAM1 P05362 1/20 0.42
SELE P16581 1/20 0.42
PKM P14618 1/20 0.40
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486670 0.88 NR4A1 (0.61) KMT2AMEN1KDM4EPOLBNR4A1
SCHEMBL6564428 0.88 KDM4E (0.56) KMT2AMEN1KDM4EPOLBSMN1; SMN2
SCHEMBL8762387 0.86 NR4A1 (0.58) KMT2AMEN1POLBNR4A1SMN1; SMN2
SCHEMBL5903678 0.85 MAOA (0.55) KMT2AMEN1KDM4ENR4A1SMN1; SMN2
SCHEMBL554765 0.85 POLB (0.64) KMT2AMEN1KDM4EPOLBSMN1; SMN2
SCHEMBL30970172 0.84 NR4A1 (0.56) KMT2AMEN1POLBNR4A1SMN1; SMN2
SCHEMBL31380 0.84 NR4A1 (0.56) KMT2AMEN1POLBNR4A1SMN1; SMN2
SCHEMBL14737907 0.80 L3MBTL1 (0.50) KMT2AMEN1NR4A1SMN1; SMN2HTR2A
SCHEMBL10350063 0.80 ALDH1A1 (0.61) KMT2AMEN1KDM4EPOLBNR4A1
SCHEMBL7185516 0.80 ALDH1A1 (0.61) KMT2AMEN1KDM4EPOLBNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405453-B1 A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) 2024-05-29 EP disclosed
CN-108884032-B Method for preparing poly (carbonate-etherimide) compounds PTT全球化学股份有限公司 2021-10-15 CN disclosed
US-10759904-B2 Method for preparing poly(carbonate-etherimide) compound PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2020-09-01 US disclosed
US-20190202980-A1 METHOD FOR PREPARING POLY(CARBONATE-ETHERIMIDE) COMPOUND PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2019-07-04 US disclosed
EP-3405453-A2 A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND PTT Global Chemical Public Company Limited (TH) 2018-11-28 EP disclosed