Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ribose (Furanose). The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | PYGM | P11217 | 3/20 | 0.38 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.37 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TK2 | O00142 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL3976341 | 1.00 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1MAPTCYP19A1 | |
| Ribose (Furanose) SCHEMBL5521544 | 0.83 | ATAD2 (0.54) | LMNAALDH1A1PYGMSLC28A1SLC28A2 | |
| Ribose (Furanose) SCHEMBL27814247 | 0.83 | DPYD (0.54) | LMNAALDH1A1MAPTPYGMSLC28A1 | |
| Ribose (Furanose) SCHEMBL1851842 | 0.83 | ATAD2 (0.54) | LMNAALDH1A1PYGMSLC28A1SLC28A2 | |
| D-Galactose SCHEMBL16581344 | 0.82 | ATAD2 (0.53) | ALDH1A1PYGMATM | |
| Dextrose SCHEMBL6692229 | 0.82 | ATAD2 (0.53) | ALDH1A1PYGMATM | |
| Ribose (Furanose) SCHEMBL9621710 | 0.82 | SLC5A2 (0.39) | ALDH1A1PYGMSLC28A1SLC28A2SLC29A1 | |
| 5-Fluorouridine SCHEMBL6441323 | 0.81 | PYGM (0.60) | LMNASMN1; SMN2MAPTTSHRHBB | |
| Fluorouracil SCHEMBL8778444 | 0.80 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1MAPTCYP19A1 | |
| Fluorouracil SCHEMBL4289411 | 0.80 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1MAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |
| US-20110104754-A1 | CELL CULTURE MEDIUM | GENETIX LIMITED | 2011-05-05 | — | — | US | disclosed |
| EP-1818392-B1 | Cell culture medium | GENETIX LTD (GB) | 2010-08-25 | — | — | EP | disclosed |
| US-20070212778-A1 | Cell culture medium | GENETIX LIMITED | 2007-09-13 | — | — | US | disclosed |
| EP-1818392-A1 | Cell culture medium | Genetix Limited (GB) | 2007-08-15 | — | — | EP | disclosed |