SCHEMBL20568014

SCHEMBL20568014

COc1ccc(S(=O)(=O)Nc2ccccc2NC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
GAA P10253 3/20 0.65
MAPT P10636 3/20 0.65
KDM4E B2RXH2 2/20 0.65
LMNA P02545 7/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
TSHR P16473 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
KEAP1 Q14145 2/20 0.60
HTT P42858 2/20 0.56
TP53 P04637 1/20 0.56
HPGD P15428 1/20 0.56
TUBB4A P04350 1/20 0.55
TUBB P07437 1/20 0.55
TUBA3C P0DPH7 1/20 0.55
TUBA1B P68363 1/20 0.55
TUBA4A P68366 1/20 0.55
TUBB4B P68371 1/20 0.55
TUBB3 Q13509 1/20 0.55
TUBB2A Q13885 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20567802 0.91 LMNA (0.74) ALDH1A1GAAMAPTKDM4ELMNA
SCHEMBL17102981 0.89 SMN1; SMN2 (0.61) ALDH1A1GAAMAPTLMNASMN1; SMN2
SCHEMBL29440572 0.89 ALDH1A1 (0.58) ALDH1A1GAAMAPTKDM4ELMNA
SCHEMBL20568982 0.89 LMNA (0.70) ALDH1A1MAPTKDM4ELMNASMN1; SMN2
SCHEMBL21987760 0.89 LMNA (0.70) ALDH1A1MAPTKDM4ELMNASMN1; SMN2
SCHEMBL5955478 0.86 ALDH1A1 (0.67) ALDH1A1GAAMAPTKDM4ELMNA
SCHEMBL29895855 0.86 ALDH1A1 (0.67) ALDH1A1GAAMAPTKDM4ELMNA
SCHEMBL8724554 0.85 L3MBTL1 (0.81) ALDH1A1GAAMAPTKDM4ELMNA
SCHEMBL23141057 0.85 ALDH1A1 (0.59) ALDH1A1GAAMAPTKDM4ELMNA
SCHEMBL20567807 0.85 LMNA (0.65) ALDH1A1MAPTKDM4ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11926168-B2 Non-phenolic color developer and heat-sensitive recording material PAPIERFABRIK AUGUST KOEHLER SE (DE) 2024-03-12 US disclosed
EP-3630496-B1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL KOEHLER PAPER SE (DE) 2022-10-26 EP disclosed
EP-3730306-B1 NON-PHENOLIC COLOUR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL KOEHLER SE AUGUST PAPIERFABRIK (DE) 2022-03-16 EP disclosed
EP-3730306-A1 NON-PHENOLIC COLOUR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL Papierfabrik August Koehler SE (DE) 2020-10-28 EP disclosed
US-20200172477-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2020-06-04 US disclosed
EP-3630496-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL Papierfabrik August Koehler SE (DE) 2020-04-08 EP disclosed
WO-2018215287-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2018-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172477-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL TDO2, SCO2, SCN1A ALDH1A1 312/4885GAA 4172/4885MAPT 2275/4885
US-11926168-B2 Non-phenolic color developer and heat-sensitive recording material TDO2, SCO2, SCN1A ALDH1A1 306/4885GAA 4170/4885MAPT 2261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.