Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IL18 | Q14116 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30427245 | 1.00 | PARP15 (0.43) | PARP15PARP10PARP2MAPTRAB9A | |
| SCHEMBL1232549 | 0.86 | ALDH1A1 (0.38) | MAPTRAB9AKDM4EPOLBPKM | |
| SCHEMBL28889487 | 0.84 | PARP15 (0.43) | PARP15PARP10PARP2MAPTRAB9A | |
| Acetic Acid SCHEMBL28488605 | 0.83 | PARP15 (0.44) | PARP15PARP10PARP2MAPTRAB9A | |
| SCHEMBL7857213 | 0.83 | MMP1 (0.39) | ALDH1A1PTGER4MMP2 | |
| SCHEMBL7863841 | 0.83 | PTGS2 (0.38) | ALDH1A1MMP2 | |
| SCHEMBL21241616 | 0.82 | CACNA1G (0.41) | PARP15PARP10PARP2MAPTRAB9A | |
| SCHEMBL16585049 | 0.82 | ALDH1A1 (0.42) | MAPTRAB9APOLBPKMKMT2A | |
| SCHEMBL2177944 | 0.81 | PKM (0.40) | MAPTRAB9AKDM4EMEN1LMNA | |
| SCHEMBL29011876 | 0.80 | FFAR1 (0.42) | PARP15PARP10PARP2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591355-B | Preparation method of clenbuterol | 苏州东瑞制药有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-114591355-A | Preparation method of clitorium | 苏州东瑞制药有限公司 | 2022-06-07 | — | — | CN | claimed |
| US-20200190120-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2020-06-18 | — | — | US | claimed |
| WO-2018216032-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2018-11-29 | — | — | WO | claimed |
| CN-114591355-B | Preparation method of clenbuterol | 苏州东瑞制药有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-114591355-B | Preparation method of clenbuterol | 苏州东瑞制药有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-114591355-A | Preparation method of clitorium | 苏州东瑞制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114591355-A | Preparation method of clitorium | 苏州东瑞制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| US-10981939-B2 | Process for the preparation of 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl) oxy] benzonitrile (Crisaborole) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2021-04-20 | — | — | US | disclosed |
| US-10865217-B2 | Process for the preparation of 5-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and polymorphs thereof | MSN LABORATORIES PRIVATE LIMITED, R & D CENTER (IN) | 2020-12-15 | — | — | US | disclosed |
| US-10865217-B2 | Process for the preparation of 5-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and polymorphs thereof | MSN LABORATORIES PRIVATE LIMITED, R & D CENTER (IN) | 2020-12-15 | — | — | US | disclosed |
| US-20200190120-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2020-06-18 | — | — | US | disclosed |
| US-20200190120-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2020-06-18 | — | — | US | disclosed |
| US-20200062785-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-[(1-HYDROXY-1,3-DIHYDRO-2,1-BENZOXABOROL-5-YL) OXY] BENZONITRILE (CRISABOROLE) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD., (IN) | 2020-02-27 | — | — | US | disclosed |
| WO-2018216032-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2018-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10865217-B2 | Process for the preparation of 5-(4-cyanophenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and polymorphs thereof | CYP1B1, CYP4B1, CYP1A1 | PARP15 1412/4885PARP10 2311/4885PARP2 1564/4885 |
| US-20200062785-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-[(1-HYDROXY-1,3-DIHYDRO-2,1-BENZOXABOROL-5-YL) OXY] BENZONITRILE (CRISABOROLE) | CYP4B1, CYP8B1, CYP4X1 | PARP15 2149/4885PARP10 3031/4885PARP2 2340/4885 |
| US-20200190120-A1 | PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF | CYP1B1, CYP4B1, CYP1A1 | PARP15 1412/4885PARP10 2311/4885PARP2 1564/4885 |
| US-10981939-B2 | Process for the preparation of 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl) oxy] benzonitrile (Crisaborole) | CYP4B1, CYP8B1, SQLE | PARP15 1896/4885PARP10 3047/4885PARP2 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.