Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12527313 | 0.84 | TDP1 (0.33) | TDP1 | |
| SCHEMBL1937378 | 0.81 | APLNR (0.30) | — | |
| SCHEMBL674128 | 0.79 | CPB1 (0.34) | NOS1NOS3NOS2 | |
| SCHEMBL6804922 | 0.77 | NOS1 (0.33) | NOS1NOS3NOS2 | |
| SCHEMBL29086267 | 0.75 | CPB1 (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL12171728 | 0.75 | MEN1 (0.35) | — | |
| SCHEMBL5968150 | 0.71 | CYP4F2 (0.32) | TDP1 | |
| SCHEMBL5828857 | 0.71 | TDP1 (0.32) | TDP1 | |
| SCHEMBL3205535 | 0.71 | NOS1 (0.34) | NOS1NOS3NOS2 | |
| SCHEMBL30874619 | 0.70 | NOS1 (0.35) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630759-A1 | ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT | Centre National De La Recherche Scientifique (FR) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018215557-A1 | ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-11-29 | — | — | WO | disclosed |