Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 4/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | CA2 | P00918 | 8/20 | 0.33 |
| ▸ | CA4 | P22748 | 4/20 | 0.33 |
| ▸ | PPIB | P23284 | 1/20 | 0.30 |
| ▸ | PPIA | P62937 | 1/20 | 0.30 |
| ▸ | PPID | Q08752 | 1/20 | 0.30 |
| ▸ | PPIG | Q13427 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668012 | 0.78 | TDP1 (0.41) | CA1CA2CA4 | |
| SCHEMBL7504982 | 0.76 | CA2 (0.49) | CA1CA2CA4PPIBPPIA | |
| SCHEMBL3748687 | 0.72 | NR1D1 (0.36) | NR1D1NR1H3CA1CA2CA4 | |
| SCHEMBL19458 | 0.71 | TDP1 (0.42) | NR1D1NR1H3CA1CA2CA4 | |
| SCHEMBL479237 | 0.70 | MTNR1A (0.46) | PPIBPPIAPPIDPPIG | |
| SCHEMBL8019716 | 0.70 | AKT1 (0.39) | — | |
| SCHEMBL8928353 | 0.70 | PPARA (0.36) | NR1D1NR1H3CA1CA2CA4 | |
| SCHEMBL12761956 | 0.70 | NR1D1 (0.34) | NR1D1NR1H3PPIBPPIAPPID | |
| SCHEMBL7562431 | 0.68 | AKT1 (0.49) | NR1D1NR1H3 | |
| SCHEMBL3778391 | 0.68 | NR1D1 (0.39) | NR1D1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160025713-A1 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS | LIFE TECHNOLOGIES CORP (US) | 2016-01-28 | — | — | US | disclosed |
| US-9164099-B2 | Site-specific labeling of affinity tags in fusion proteins | Life Technologies Corporation (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140038856-A1 | Site-specific labeling of affinity tags in fusion proteins | Life Technologies Corporation (US) | 2014-02-06 | — | — | US | disclosed |
| US-20120270757-A1 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS | Life Technologies Corporation (US) | 2012-10-25 | — | — | US | disclosed |
| US-20110021372-A1 | Compositions and methods for detection and isolation of phosphorylated molecules | Life Technologies Corporation (US) | 2011-01-27 | — | — | US | disclosed |
| US-7776533-B2 | Compositions and methods for detection and isolation of phosphorylated molecules | Life Technologies Corporation (US) | 2010-08-17 | — | — | US | disclosed |
| US-20100009381-A1 | Compositions and methods for detection and isolation of phosphorylated molecules | Life Technologies Corporation (US) | 2010-01-14 | — | — | US | disclosed |
| US-20090081722-A1 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS | INVITROGEN CORPORATION (US) | 2009-03-26 | — | — | US | disclosed |
| US-20090004641-A1 | SITE-SPECIFIC LABELING OF AFFINITY PEPTIDES IN FUSION PROTEINS | INVITROGEN CORPORATION (US) | 2009-01-01 | — | — | US | disclosed |
| US-7445894-B2 | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES, INC. (US) | 2008-11-04 | — | — | US | disclosed |
| EP-1546359-A4 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS | MOLECULAR PROBES INC (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20070054304-A1 | COMPOSITIONS AND METHODS FOR DETECTION AND ISOLATION OF PHOSPHORYLATED MOLECULES | INVITROGEN CORPORATION (US) | 2007-03-08 | — | — | US | disclosed |
| US-7102005-B2 | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES, INC. (US) | 2006-09-05 | — | — | US | disclosed |
| US-20060141554-A1 | Site-specific labeling of affinity tags in fusion proteins | INVITROGEN CORP. | 2006-06-29 | — | — | US | disclosed |
| US-20050233307-A1 | Site-specific labeling of affinity tags in fusion proteins | Life Technologies Corporation | 2005-10-20 | — | — | US | disclosed |
| EP-1546359-A2 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS | Molecular Probes Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| US-20050014197-A1 | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES, INC. | 2005-01-20 | — | — | US | disclosed |
| US-20040171034-A1 | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES, INC. | 2004-09-02 | — | — | US | disclosed |
| WO-2004025259-A2 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS | MOLECULAR PROBES, INC. (US) | 2004-03-25 | — | — | WO | disclosed |
| US-20040038306-A1 | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES, INC. | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060141554-A1 | Site-specific labeling of affinity tags in fusion proteins | APBA1, F13A1, F13B | NR1D1 3418/4885NR1H3 3709/4885CA1 204/4885 |
| US-20160025713-A1 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS | APBA1, F13A1, F13B | NR1D1 3418/4885NR1H3 3709/4885CA1 204/4885 |
| US-20090004641-A1 | SITE-SPECIFIC LABELING OF AFFINITY PEPTIDES IN FUSION PROTEINS | APBA1, F13A1, HM13 | NR1D1 3419/4885NR1H3 3861/4885CA1 187/4885 |
| US-20120270757-A1 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS | APBA1, NAPA, F13B | NR1D1 3202/4885NR1H3 3664/4885CA1 341/4885 |
| US-20090081722-A1 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS | APBA1, F13A1, F13B | NR1D1 3418/4885NR1H3 3709/4885CA1 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.