SCHEMBL479237

SCHEMBL479237

CC(C)(C)OC(=O)Cc1ccc(N)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
PPIB P23284 1/20 0.42
PPIA P62937 1/20 0.42
PPID Q08752 1/20 0.42
PPIG Q13427 1/20 0.42
RIPK1 Q13546 1/20 0.41
RIPK3 Q9Y572 1/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
EPHX2 P34913 1/20 0.41
ALDH1A1 P00352 2/20 0.40
GAA P10253 1/20 0.40
GFER P55789 1/20 0.40
MAPT P10636 2/20 0.39
ESRRG P62508 1/20 0.39
CYP3A4 P08684 2/20 0.38
CYP2C19 P33261 1/20 0.38
LMNA P02545 2/20 0.38
FDPS P14324 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1732992 0.86 CYP4F2 (0.46) MTNR1AMTNR1BRIPK1RIPK3CYP4F2
SCHEMBL5866843 0.85 LOXL2 (0.46) MTNR1AMTNR1BRIPK1RIPK3CYP4F2
SCHEMBL1578976 0.84 PPIB (0.46) PPIBPPIAPPIDPPIGEPHX2
SCHEMBL21554546 0.83 CA2 (0.50) MTNR1AMTNR1BEPHX2ALDH1A1GAA
SCHEMBL19085086 0.83 MTNR1A (0.47) MTNR1AMTNR1BRIPK1RIPK3CYP4F2
SCHEMBL1283948 0.83 CA2 (0.50) MTNR1AMTNR1BRIPK1RIPK3CYP4F2
SCHEMBL7517689 0.83 HPGD (0.50) MTNR1AMTNR1BRIPK1RIPK3CYP4F2
SCHEMBL12270169 0.82 MTNR1A (0.43) MTNR1AMTNR1BALDH1A1MAPT
SCHEMBL7322522 0.82 CYP4F2 (0.44) PPIBPPIAPPIDPPIGCYP4F2
SCHEMBL4961300 0.82 MTNR1A (0.47) MTNR1AMTNR1BRIPK1RIPK3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115895047-B Ratio fluorescent composite film material for biogenic amine detection and preparation method thereof 南通大学 2024-05-10 CN claimed
CN-115895047-A Ratiometric fluorescence composite film material for biogenic amine detection and preparation method thereof 南通大学 2023-04-04 CN claimed
US-12559492-B2 BRAF degraders C4 THERAPEUTICS, INC. (US) 2026-02-24 US disclosed
US-20260042782-A1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR C4 THERAPEUTICS, INC. (US) 2026-02-12 US disclosed
EP-4681715-A2 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR C4 Therapeutics, Inc. (US) 2026-01-21 EP disclosed
EP-4076450-B1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR C4 THERAPEUTICS INC (US) 2025-12-10 EP disclosed
US-12486290-B2 Isoindolinone and indazole compounds for the degradation of EGFR C4 THERAPEUTICS, INC. (US) 2025-12-02 US disclosed
US-20250270234-A1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR C4 THERAPEUTICS, INC. (US) 2025-08-28 US disclosed
US-12371442-B2 Isoindolinone and indazole compounds for the degradation of EGFR C4 THERAPEUTICS, INC. (US) 2025-07-29 US disclosed
WO-2025129124-A1 STIMULI-RESPONSIVE STING-ACTIVATING POLYMER COMPOSITIONS AND METHODS OF USE THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-06-19 WO disclosed
WO-2025100889-A1 QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 한국화학연구원 2025-05-15 WO disclosed
US-20030153596-A1 Novel thiourea derivatives and the pharmaceutical compositions containing the same PACIFIC CORPORATION (KR) 2003-08-14 US disclosed
US-20030083267-A1 Cell adhesion inhibitors BIOGEN, INC., A MASSACHUSETTS CORPORATION 2003-05-01 US disclosed
US-20030018016-A1 Cell adhesion inhibitors BIOGEN IDEC MA, INC. 2003-01-23 US disclosed
EP-0805796-B1 CELL ADHESION INHIBITORS BIOGEN INC (US) 2002-12-11 EP disclosed
US-6376538-B1 ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASES BIOGEN, INC. 2002-04-23 US disclosed
US-6306840-B1 ANTISTICKING AGENTS OF OLIGOPEPTIDES BIOGEN, INC. 2001-10-23 US disclosed
EP-1142867-A2 Cell adhesion inhibitors BIOGEN, INC. (US) 2001-10-10 EP disclosed
EP-0805796-A1 CELL ADHESION INHIBITORS BIOGEN, INC. (US) 1997-11-12 EP disclosed
WO-1996022966-A1 CELL ADHESION INHIBITORS BIOGEN, INC. (US) 1996-08-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030153596-A1 Novel thiourea derivatives and the pharmaceutical compositions containing the same TAS2R40, TAS1R2, TAS2R45 MTNR1A 65/4885MTNR1B 179/4885PPIB 1756/4885
US-12559492-B2 BRAF degraders BRAF, NRAS, HRAS MTNR1A 1454/4885MTNR1B 1229/4885PPIB 3946/4885
US-12486290-B2 Isoindolinone and indazole compounds for the degradation of EGFR EGFR, ERBB2, ERBB3 MTNR1A 2395/4885MTNR1B 2613/4885PPIB 2159/4885
US-20030083267-A1 Cell adhesion inhibitors ICAM1, VCAM1, EPCAM MTNR1A 3249/4885MTNR1B 2117/4885PPIB 1459/4885
US-20250270234-A1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR EGFR, ERBB2, ERBB3 MTNR1A 2395/4885MTNR1B 2613/4885PPIB 2159/4885
US-20260042782-A1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR EGFR, ERBB2, ERBB3 MTNR1A 3488/4885MTNR1B 3426/4885PPIB 2400/4885
US-20030018016-A1 Cell adhesion inhibitors ICAM1, VCAM1, EPCAM MTNR1A 3249/4885MTNR1B 2117/4885PPIB 1459/4885
US-12371442-B2 Isoindolinone and indazole compounds for the degradation of EGFR EGFR, ERBB2, ERBB3 MTNR1A 2395/4885MTNR1B 2613/4885PPIB 2159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.