Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743205 | 0.83 | PTGS2 (0.33) | KMT2ALMNAHSD11B1 | |
| SCHEMBL16417101 | 0.74 | LMNA (0.41) | LMNA | |
| SCHEMBL2395249 | 0.69 | PARP1 (0.38) | KMT2APARP1OPRK1HSD11B1HPGD | |
| SCHEMBL16599817 | 0.63 | HTR2A (0.33) | HDAC4LMNAHDAC6 | |
| SCHEMBL4831942 | 0.61 | CCR2 (0.36) | HDAC4PKMALDH1A1HSD11B1HPGD | |
| SCHEMBL9851147 | 0.60 | NPC1 (0.37) | KMT2ANPC1ALDH1A1LMNAHSD11B1 | |
| SCHEMBL8952460 | 0.60 | HDAC6 (0.50) | ALDH1A1LMNAHSD11B1HDAC1HDAC6 | |
| SCHEMBL3048130 | 0.60 | SMN1; SMN2 (0.51) | — | |
| SCHEMBL8699921 | 0.60 | CACNA1B (0.65) | KMT2APKMCACNA1B | |
| SCHEMBL28316797 | 0.60 | KDM1A (0.46) | HDAC4NPC1PKMOPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |