SCHEMBL2057487

SCHEMBL2057487

CC[Si](CC)(CC)c1cc(C)ccc1S(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.37
GAA P10253 2/20 0.37
RAPGEF4 Q8WZA2 1/20 0.37
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
HIF1A Q16665 1/20 0.35
POLB P06746 3/20 0.35
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 3/20 0.35
RECQL P46063 2/20 0.35
MEP1B Q16820 2/20 0.35
MEN1 O00255 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
CASP6 P55212 1/20 0.35
ELAVL1 Q15717 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MPL P40238 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2057913 0.87 GAA (0.36) HSD17B10GAARAPGEF4LMNAHPGD
SCHEMBL2687440 0.86 HSD17B10 (0.37) HSD17B10GAARAPGEF4LMNAHPGD
SCHEMBL2057292 0.85 HSD17B10 (0.36) HSD17B10GAARAPGEF4LMNAHPGD
SCHEMBL2058146 0.84 POLB (0.38) HSD17B10GAARAPGEF4LMNAHPGD
SCHEMBL2058245 0.82 ALDH1A1 (0.35) HSD17B10GAARAPGEF4LMNAPOLB
SCHEMBL2057900 0.82 POLB (0.39) GAALMNAHPGDPOLBKMT2A
SCHEMBL8633298 0.81 TSHR (0.35) HSD17B10LMNAHPGDHIF1AKMT2A
SCHEMBL2057737 0.81 TRPA1 (0.36) HSD17B10LMNAHPGDHIF1APOLB
SCHEMBL2057576 0.81 LMNA (0.35) HSD17B10GAARAPGEF4LMNAHPGD
SCHEMBL2059565 0.81 GAA (0.34) HSD17B10GAARAPGEF4HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9065146-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2015-06-23 US disclosed
US-8551662-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2013-10-08 US disclosed
US-8029935-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2011-10-04 US disclosed
US-20110229771-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2011-09-22 US disclosed
US-7981553-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-19 US disclosed
US-20110159380-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2011-06-30 US disclosed
US-20100227226-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-09-09 US disclosed
US-20100021823-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-01-28 US disclosed
US-7575833-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2009-08-18 US disclosed
US-20070238025-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-11 US disclosed
US-7223502-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2007-05-29 US disclosed
US-20050118512-A1 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-06-02 US disclosed
US-5847218-A Sulfonium salts and chemically amplified positive resist compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed