SCHEMBL2059565

SCHEMBL2059565

C=CC[Si](CC=C)(CC=C)c1cc(C)ccc1S(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.34
HSD17B10 Q99714 2/20 0.34
HPGD P15428 2/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
POLB P06746 2/20 0.32
RECQL P46063 2/20 0.32
KMT2A Q03164 2/20 0.32
MEP1B Q16820 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.32
CASP6 P55212 1/20 0.32
ELAVL1 Q15717 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
RCE1 Q9Y256 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2057640 0.87 GAA (0.33) GAAHSD17B10HPGDKDM4EALDH1A1
SCHEMBL2057487 0.81 HSD17B10 (0.37) GAAHSD17B10HPGDKDM4EALDH1A1
SCHEMBL2057913 0.78 GAA (0.36) GAAHSD17B10HPGDKDM4EALDH1A1
SCHEMBL2057858 0.78 GAA (0.36) GAAHSD17B10KDM4EALDH1A1MAPT
SCHEMBL2058245 0.77 ALDH1A1 (0.35) GAAHSD17B10KDM4EALDH1A1MAPT
SCHEMBL2058146 0.76 POLB (0.38) GAAHSD17B10HPGDKDM4EALDH1A1
SCHEMBL939874 0.75 GAA (0.40) GAAHSD17B10HPGDKDM4EALDH1A1
SCHEMBL2057743 0.75 TDP1 (0.37) GAAHSD17B10HPGDKDM4EALDH1A1
Water SCHEMBL3135477 0.74 GAA (0.39) GAAHSD17B10HPGDKDM4EALDH1A1
SCHEMBL2057900 0.74 POLB (0.39) GAAHPGDKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108884181-B Photocurable compositions containing electron poor olefins 汉高知识产权控股有限责任公司 2021-05-11 CN disclosed
US-9065146-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2015-06-23 US disclosed
US-8551662-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2013-10-08 US disclosed
US-8029935-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2011-10-04 US disclosed
US-20110229771-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2011-09-22 US disclosed
US-7981553-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-19 US disclosed
US-20110159380-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2011-06-30 US disclosed
US-20100227226-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-09-09 US disclosed
US-20100021823-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-01-28 US disclosed
US-7575833-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2009-08-18 US disclosed
EP-1747209-A4 A FACILE METHOD FOR SYNTHESIZING BACCATIN III COMPOUNDS IMMUNOGEN INC (US) 2007-12-12 EP disclosed
US-20070238025-A1 NONAQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-11 US disclosed
US-7223502-B2 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2007-05-29 US disclosed
US-7186851-B2 Facile method for synthesizing baccatin III compounds IMMUNOGEN, INC. (US) 2007-03-06 US disclosed
EP-1747209-A1 A FACILE METHOD FOR SYNTHESIZING BACCATIN III COMPOUNDS Immunogen, Inc. (US) 2007-01-31 EP disclosed
WO-2005113528-A1 A FACILE METHOD FOR SYNTHESIZING BACCATIN III COMPOUNDS IMMUNOGEN, INC. (US) 2005-12-01 WO disclosed
US-20050256323-A1 Facile method for synthesizing baccatin III compounds IMMUNOGEN, INC. 2005-11-17 US disclosed
US-20050118512-A1 Nonaqueous electrolyte and lithium secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050256323-A1 Facile method for synthesizing baccatin III compounds PTMA, BBOX1, TBXAS1 GAA 1923/4885HSD17B10 577/4885HPGD 469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.