Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049708 | 0.79 | RAPGEF4 (0.33) | RAPGEF4KDM4EL3MBTL1 | |
| SCHEMBL8635370 | 0.79 | KMT2A (0.39) | RAPGEF4KDM4EL3MBTL1 | |
| SCHEMBL15003249 | 0.78 | POLB (0.40) | — | |
| SCHEMBL532742 | 0.77 | RAPGEF4 (0.34) | RAPGEF4 | |
| SCHEMBL2290449 | 0.74 | ALDH1A1 (0.33) | RAPGEF4KDM4EL3MBTL1 | |
| SCHEMBL760815 | 0.74 | RAPGEF4 (0.45) | RAPGEF4KDM4E | |
| SCHEMBL7456451 | 0.73 | RAPGEF4 (0.39) | RAPGEF4L3MBTL1 | |
| SCHEMBL14682851 | 0.73 | ALDH1A1 (0.46) | KDM4EL3MBTL1 | |
| SCHEMBL11840512 | 0.72 | ACHE (0.35) | — | |
| SCHEMBL1109760 | 0.72 | RAPGEF4 (0.43) | RAPGEF4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630779-A1 | ANTIBIOTIC RESISTANCE BREAKERS | Kings College London (GB) | 2020-04-08 | — | — | EP | disclosed |
| WO-2018220365-A1 | ANTIBIOTIC RESISTANCE BREAKERS | KING'S COLLEGE LONDON (GB) | 2018-12-06 | — | — | WO | disclosed |