Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL760815 | 0.97 | RAPGEF4 (0.45) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9359704 | 0.93 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL30511867 | 0.93 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL29360453 | 0.93 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL28025504 | 0.85 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL18044240 | 0.85 | RAPGEF4 (0.38) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL28233697 | 0.83 | RAPGEF4 (0.36) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL3007305 | 0.81 | RAPGEF4 (0.39) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| Acetic Acid SCHEMBL29701127 | 0.81 | KDM4E (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL22521957 | 0.79 | ALDH1A1 (0.39) | RAPGEF4ALDH1A1TSHRCYP1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312125-A1 | Solvents containing cycloalkyl alkyl ethers and process for production of the ethers | KIM IDAN | 2008-12-18 | — | — | US | claimed |
| EP-1405840-B1 | Organometallic reaction method | ZEON CORP (JP) | 2014-08-20 | — | — | EP | disclosed |
| US-8163950-B2 | Processes for the production of tri-organo-monoalkoxysilanes and process for the production of tri-organo-monochlorosilanes | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20110275849-A1 | PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES | BANNOU TADASHI | 2011-11-10 | — | — | US | disclosed |
| US-8017813-B2 | Process for production of cycloalkyl alkyl ethers | ZEON CORPORATION (JP) | 2011-09-13 | — | — | US | disclosed |
| US-8008521-B2 | Processes for the production of tri-organo-monoalkoxysilanes and process for the production of tri-organo-monochlorosilanes | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-08-30 | — | — | US | disclosed |
| CN-1837221-B | Production processes for triorganomonochlorosilanes | HOKKO CHEM IND CO | 2011-06-08 | — | — | CN | disclosed |
| EP-2279995-A2 | Process for producing cycloalkyl alkyl ethers | Zeon Corporation (JP) | 2011-02-02 | — | — | EP | disclosed |
| CN-100509734-C | Solvent containing cycloalkyl alkyl ether and preparation method thereof | NIPPON ZEON CO (JP) | 2009-07-08 | — | — | CN | disclosed |
| US-20090082585-A1 | PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES | BANNOU TADASHI | 2009-03-26 | — | — | US | disclosed |
| CN-1323100-C | Process for preparing a melt-processable polyamide composition | DSM IP ASSETS BV (NL) | 2007-06-27 | — | — | CN | disclosed |
| CN-1296374-C | Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes | HOKKO CHEM IND CO (JP) | 2007-01-24 | — | — | CN | disclosed |
| CN-1837221-A | Production processes for triorganomonochlorosilanes | HOKKO CHEM IND CO (JP) | 2006-09-27 | — | — | CN | disclosed |
| CN-1753934-A | Be used to prepare the method for the daiamid composition of melt-processable | DSM IP ASSETS BV (NL) | 2006-03-29 | — | — | CN | disclosed |
| CN-1751079-A | The method of the daiamid composition of preparation melt-processable | DSM IP ASSETS BV (NL) | 2006-03-22 | — | — | CN | disclosed |
| CN-1612886-A | Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes | HOKKO CHEM IND CO (JP) | 2005-05-04 | — | — | CN | disclosed |
| US-20050070730-A1 | Production processes for triorganomonoalkoxysilanes and triorganomonochlorosilanes | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-31 | — | — | US | disclosed |
| US-20050065060-A1 | Solvents containing cycloakyl alkyl ethers and process for production of the ethers | ZEON CORPORATION (JP) | 2005-03-24 | — | — | US | disclosed |
| CN-1543449-A | Solvent containing cycloalkyl alkyl ether and preparation method thereof | �ձ�������ʽ���� | 2004-11-03 | — | — | CN | disclosed |
| EP-1405840-A1 | SOLVENTS CONTAINING CYCLOALKYL ALKYL ETHERS AND PROCESS FOR PRODUCTION OF THE ETHERS | Zeon Corporation (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312125-A1 | Solvents containing cycloalkyl alkyl ethers and process for production of the ethers | CBR1, ADH1C, ECH1 | RAPGEF4 526/4885ALDH1A1 271/4885KDM4E 687/4885 |
| US-20110275849-A1 | PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES | MLX, HAX1, RPS4X | RAPGEF4 3785/4885ALDH1A1 2163/4885KDM4E 1563/4885 |
| US-20090082585-A1 | PROCESSES FOR THE PRODUCTION OF TRI-ORGANO-MONOALKOXYSILANES AND PROCESS FOR THE PRODUCTION OF TRI-ORGANO-MONOCHLOROSILANES | MLX, HAX1, RPS4X | RAPGEF4 3785/4885ALDH1A1 2163/4885KDM4E 1563/4885 |
| US-20050070730-A1 | Production processes for triorganomonoalkoxysilanes and triorganomonochlorosilanes | MLX, HAX1, GRIA3 | RAPGEF4 3024/4885ALDH1A1 2839/4885KDM4E 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.