Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 6/20 | 0.36 |
| ▸ | MMP3 | P08254 | 6/20 | 0.36 |
| ▸ | MMP7 | P09237 | 6/20 | 0.36 |
| ▸ | MMP1 | P03956 | 5/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058327 | 1.00 | FKBP1A (0.36) | FKBP1AMMP2MMP3MMP7MMP1 | |
| SCHEMBL2057762 | 1.00 | FKBP1A (0.36) | FKBP1AMMP2MMP3MMP7MMP1 | |
| SCHEMBL2057726 | 0.94 | MMP3 (0.36) | FKBP1AMMP2MMP3MMP7MMP1 | |
| SCHEMBL2058089 | 0.94 | MMP3 (0.36) | FKBP1AMMP2MMP3MMP7MMP1 | |
| SCHEMBL2057725 | 0.94 | MMP3 (0.36) | FKBP1AMMP2MMP3MMP7MMP1 | |
| SCHEMBL3414464 | 0.79 | FKBP1A (0.39) | FKBP1A | |
| SCHEMBL6048244 | 0.76 | FKBP1A (0.36) | FKBP1A | |
| SCHEMBL2057797 | 0.75 | FKBP1A (0.36) | FKBP1A | |
| SCHEMBL2058320 | 0.75 | FKBP1A (0.36) | FKBP1A | |
| SCHEMBL2057754 | 0.75 | FKBP1A (0.36) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258320-B2 | N alkylcarbonyl amino lactone compounds and their use | WEI EDWARD TAK (US) | 2012-09-04 | — | — | US | disclosed |
| US-20120184608-A1 | N alkylcarbonyl amino lactone compounds and their use | WEI EDWARD TAK (US) | 2012-07-19 | — | — | US | disclosed |
| US-20110160303-A1 | N-ALKYLCARBONYL-AMINO ACID ESTER AND N-ALKYLCARBONYL-AMINO LACTONE COMPOUNDS AND THEIR USE | EDWARD TAK WEI | 2011-06-30 | — | — | US | disclosed |
| US-20080227857-A1 | N-Alkylcarbonyl-Amino Acid Ester and N-Alkylcarbonyl-Amino Lactone Compounds and Their Use | WEI EDWARD TAK | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184608-A1 | N alkylcarbonyl amino lactone compounds and their use | TRPA1, TRPV1, TAS2R14 | FKBP1A 2819/4885MMP2 4426/4885MMP3 4490/4885 |
| US-20080227857-A1 | N-Alkylcarbonyl-Amino Acid Ester and N-Alkylcarbonyl-Amino Lactone Compounds and Their Use | TRPA1, TRPV1, CYSLTR1 | FKBP1A 3610/4885MMP2 4145/4885MMP3 4136/4885 |
| US-20110160303-A1 | N-ALKYLCARBONYL-AMINO ACID ESTER AND N-ALKYLCARBONYL-AMINO LACTONE COMPOUNDS AND THEIR USE | TRPA1, TRPV1, CYSLTR1 | FKBP1A 3610/4885MMP2 4145/4885MMP3 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.