Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL2969867 | 0.84 | TSHR (0.64) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL164261 | 0.84 | TSHR (0.64) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL986326 | 0.84 | NAAA (0.59) | TSHRNAAAHDAC3 | |
| Benzoic Acid SCHEMBL5547336 | 0.81 | GRIN1 (0.47) | DAOTSHRNAPRTGRIN1GRIN2A | |
| Terephthalic Acid SCHEMBL337710 | 0.80 | TSHR (0.60) | DAOTSHRNAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL20240890 | 0.80 | TSHR (0.60) | DAOTSHRNAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL17835406 | 0.80 | TSHR (0.60) | DAOTSHRNAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL7046508 | 0.80 | TSHR (0.60) | DAOTSHRNAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL28803923 | 0.80 | TSHR (0.60) | DAOTSHRNAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL6453701 | 0.80 | TSHR (0.60) | DAOTSHRNAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746510-B1 | USE OF POLYVALENT ALCOHOLS FOR INCREASING WELD LINE STRENGTH AFTER HEAT AGEING IN POLYAMIDES | BASF SE (DE) | 2024-01-31 | — | — | EP | disclosed |
| EP-3746510-A1 | USE OF POLYHYRIC ALCOHOLS FOR INCREASING THE IMPACT STRENGTH OF A WELDING SEAM AFTER HEAT AGING IN POLYAMIDES | BASF SE (DE) | 2020-12-09 | — | — | EP | disclosed |
| EP-3728437-A1 | POLYAMIDE MOULDING COMPOUNDS WITH IMPROVED OPTICAL PROPERTIES AND USE OF COLOURANTS THEREIN | BASF SE (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3714004-A1 | POLYAMIDE COMPOSITION FOR THE PRODUCTION OF WELDABLE MOULDED BODIES | BASF SE (DE) | 2020-09-30 | — | — | EP | disclosed |
| WO-2019149791-A1 | USE OF POLYHYRIC ALCOHOLS FOR INCREASING THE IMPACT STRENGTH OF A WELDING SEAM AFTER HEAT AGING IN POLYAMIDES | BASF SE (DE) | 2019-08-08 | — | — | WO | disclosed |
| CN-105980469-B | Polyolefin copolymer as toner in polyamide | 巴斯夫欧洲公司 | 2019-03-12 | — | — | CN | disclosed |
| EP-3420033-A1 | POLYAMIDE COMPOSITION WHICH IS DYED IN BLACK AND PRODUCTION AND USE THEREOF | BASF SE (DE) | 2019-01-02 | — | — | EP | disclosed |
| CN-105980469-A | Polyolefin copolymers as color enhancers in polyamides | 巴斯夫欧洲公司 | 2016-09-28 | — | — | CN | disclosed |