Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 7/20 | 0.74 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.74 |
| ▸ | CA1 | P00915 | 1/20 | 0.74 |
| ▸ | CA2 | P00918 | 1/20 | 0.74 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.74 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.74 |
| ▸ | ITGAL | P20701 | 1/20 | 0.74 |
| ▸ | CA4 | P22748 | 1/20 | 0.74 |
| ▸ | CA6 | P23280 | 1/20 | 0.74 |
| ▸ | ADK | P55263 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL27922533 | 0.91 | AHR (0.81) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL28087845 | 0.89 | AHR (0.77) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL28042366 | 0.89 | AHR (0.85) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL28020016 | 0.89 | AHR (0.85) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL28385617 | 0.87 | AHR (0.74) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL28306370 | 0.87 | AHR (0.74) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL399069 | 0.87 | AHR (0.74) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL27957692 | 0.86 | AHR (0.90) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL30463845 | 0.86 | — | — | |
| Indole SCHEMBL29352896 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486777-A | Indoloethylamine derivative and preparation method and application thereof | 浙江中医药大学 | 2024-02-02 | — | — | CN | claimed |
| US-20110159068-A1 | Osteogenic composition comprising a growth factor/amphiphilic polymer complex, a soluble cation salt and an organic support | ADOCIA (FR) | 2011-06-30 | — | — | US | claimed |
| US-20090291114-A1 | OSTEOGENIC COMPOSITION COMPRISING A GROWTH FACTOR/AMPHIPHILIC POLYMER COMPLEX, A SOLUBLE CATION SALT AND AN ORGANIC SUPPORT | ADOCIA (FR) | 2009-11-26 | — | — | US | claimed |
| CN-119798255-A | 1-Thienyl-beta-carboline IDO1 and TDO dual inhibitor and medical application thereof | 南京医科大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-117486777-A | Indoloethylamine derivative and preparation method and application thereof | 浙江中医药大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-100420672-C | Selective COX-2 inhibitory novel esters from indolealkanols and novel amides from indolealkylamines | UNIV VANDERBILT (US) | 2008-09-24 | — | — | CN | disclosed |
| CN-100418968-C | Pirazino(aza)indole derivatives | VERNALIS RES LTD (GB) | 2008-09-17 | — | — | CN | disclosed |
| CN-1289499-C | Pyrazino (aza) indole derivatives | VERNALIS RES LTD (GB) | 2006-12-13 | — | — | CN | disclosed |
| US-7145009-B2 | Pirazino(aza)indole derivatives | VERNALIS RESEARCH LIMITED (GB) | 2006-12-05 | — | — | US | disclosed |
| CN-1837207-A | Pirazino(aza)indole derivatives | VERNALIS RES LTD (GB) | 2006-09-27 | — | — | CN | disclosed |
| US-20060160816-A1 | Pirazino(AZA) indole derivatives | VERNALIS RESEARCH LIMITED | 2006-07-20 | — | — | US | disclosed |
| EP-0623138-A1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | UNION PHARMA SCIENT APPL (FR) | 1994-11-09 | — | — | EP | disclosed |
| WO-1994023720-A1 | TETRAHYDRO-BETA-CARBOLINES | ELI LILLY AND COMPANY (US) | 1994-10-27 | — | — | WO | disclosed |
| WO-1994024132-A1 | TETRAHYDRO-PYRIDO-INDOLE | ELI LILLY AND COMPANY (US) | 1994-10-27 | — | — | WO | disclosed |
| EP-0620223-A2 | Tetrahydro-pyrido-indole | ELI LILLY AND COMPANY (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0620222-A2 | Tetrahydro-beta-carbolines | ELI LILLY AND COMPANY (US) | 1994-10-19 | — | — | EP | disclosed |
| US-5300645-A | Condensation of cycloalkyl-, phenyl- or naphthylpyrrole ethylamines with a 2-oxazolidinone to get antiserotonine agent | ELI LILLY AND COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| WO-1993014102-A1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRES UPSA (FR) | 1993-07-22 | — | — | WO | disclosed |
| CN-1015054-B | N-INDOLYLETHYL SULPHONIC ACID AMIDES, PROCESS FOR PREPARATION THEREOF AND THEIR USE | BAYER AG (DE) | 1991-12-11 | — | — | CN | disclosed |
| CN-86102761-A | N-indyl ethyl-sulfonamides Preparation Method And The Use | — | 1987-02-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291114-A1 | OSTEOGENIC COMPOSITION COMPRISING A GROWTH FACTOR/AMPHIPHILIC POLYMER COMPLEX, A SOLUBLE CATION SALT AND AN ORGANIC SUPPORT | BMP2, SOST, BMP1 | AHR 3378/4885TRPA1 3200/4885CA1 62/4885 |
| US-20060160816-A1 | Pirazino(AZA) indole derivatives | PIR, GPR119, INMT | AHR 51/4885TRPA1 338/4885CA1 1874/4885 |
| US-20110159068-A1 | Osteogenic composition comprising a growth factor/amphiphilic polymer complex, a soluble cation salt and an organic support | BMP2, SOST, BMP1 | AHR 3677/4885TRPA1 2965/4885CA1 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.