SCHEMBL20613635

SCHEMBL20613635

CNCCNC(=O)CC(C)(C)CO

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PTGS1 P23219 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20613663 0.84 MEN1 (0.50) NAAAALDH1A1MEN1KMT2A
SCHEMBL12335208 0.84 MEN1 (0.35) NAAAALDH1A1MEN1KMT2A
SCHEMBL22236865 0.83 CNR1 (0.37) NAAAALDH1A1MEN1KMT2APTGS1
SCHEMBL20613710 0.82 MCL1 (0.44) NAAAMEN1KMT2A
SCHEMBL21164341 0.81 HPGD (0.42) ALDH1A1MEN1KMT2A
SCHEMBL20613667 0.81 CASP2 (0.48) NAAAALDH1A1KMT2A
SCHEMBL19827537 0.80 PTGS1 (0.49) NAAAALDH1A1MEN1KMT2APTGS1
SCHEMBL20613631 0.79 ADH1B (0.34) NAAAMEN1KMT2A
SCHEMBL12308816 0.79 ALDH1A1 (0.36) ALDH1A1
SCHEMBL18436000 0.79 PIK3CD (0.44) NAAAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3215496-B1 PANTOTHENAMIDE ANALOGUES RADBOUD UNIV MEDISCH CENTRUM (NL) 2019-01-02 EP disclosed