Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 4/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30376090 | 0.87 | L3MBTL1 (0.77) | L3MBTL1KDM4EABCG2ALDH1A1MEN1 | |
| SCHEMBL19267888 | 0.87 | L3MBTL1 (0.77) | L3MBTL1KDM4EABCG2ALDH1A1MEN1 | |
| SCHEMBL8064295 | 0.83 | L3MBTL1 (0.71) | L3MBTL1KDM4EABCG2ALDH1A1MEN1 | |
| SCHEMBL8066758 | 0.82 | L3MBTL1 (0.72) | L3MBTL1KDM4EABCG2ALDH1A1MEN1 | |
| SCHEMBL29979584 | 0.82 | L3MBTL1 (0.79) | L3MBTL1KDM4EABCG2ALDH1A1MEN1 | |
| SCHEMBL1421600 | 0.78 | ABCG2 (0.67) | L3MBTL1KDM4EABCG2ALDH1A1MEN1 | |
| SCHEMBL4268322 | 0.77 | L3MBTL1 (1.00) | L3MBTL1KDM4EABCG2ALDH1A1MEN1 | |
| SCHEMBL7306849 | 0.76 | MAPT (0.74) | L3MBTL1ABCG2ALDH1A1MEN1KMT2A | |
| SCHEMBL18526951 | 0.75 | ABCG2 (0.65) | L3MBTL1KDM4EABCG2ALDH1A1MEN1 | |
| SCHEMBL738489 | 0.75 | MEN1 (0.71) | L3MBTL1ABCG2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421035-A1 | NOVEL USE OF CHROMONE DERIVATIVE AS PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING FIBROSIS BY USING EPITHELIAL-MESENCHYMAL TRANSITION INHIBITORY ACTIVITY THEREOF | Osteoneurogen Inc. (KR) | 2019-01-02 | — | — | EP | disclosed |