SCHEMBL20616751

SCHEMBL20616751

c1ccc(-n2c3ccccc3n3c4ccc5c6ccccc6[nH]c5c4nc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.40
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
TP53 P04637 1/20 0.37
PDE7A Q13946 2/20 0.37
PDE7B Q9NP56 2/20 0.37
GABRP O00591 3/20 0.36
GABRD O14764 3/20 0.36
GABRA1 P14867 3/20 0.36
GABRB1 P18505 3/20 0.36
GABRG2 P18507 3/20 0.36
GABRB3 P28472 3/20 0.36
GABRA5 P31644 3/20 0.36
GABRA3 P34903 3/20 0.36
GABRA2 P47869 3/20 0.36
GABRB2 P47870 3/20 0.36
GABRA4 P48169 3/20 0.36
GABRE P78334 3/20 0.36
GABRA6 Q16445 3/20 0.36
GABRG1 Q8N1C3 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24666931 0.87 KIF11 (0.39) KIF11LMNAMAPTTP53GABRP
SCHEMBL20616881 0.81 NQO2 (0.42) KIF11LMNAMAPTTP53PDE7A
SCHEMBL26234614 0.79 KDM4E (0.34) PDE7APDE7BGABRPGABRDGABRA1
SCHEMBL26234609 0.79 KDM4E (0.34) PDE7APDE7BGABRPGABRDGABRA1
SCHEMBL20616742 0.78 NQO2 (0.44) KIF11LMNAMAPTTP53PDE7A
SCHEMBL18934894 0.78 NQO2 (0.44) KIF11LMNAMAPTTP53PDE7A
SCHEMBL23652463 0.77 ADORA2B (0.34) KIF11LMNAMAPTTP53PDE7A
SCHEMBL24367781 0.76 L3MBTL1 (0.46) MAPTCYP1A2ADORA2BADORA1KDM4E
SCHEMBL18934858 0.75 AHR (0.41) KIF11MAPTPDE7APDE7BGABRP
SCHEMBL18934354 0.75 AHR (0.41) KIF11MAPTPDE7APDE7BGABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230329089-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-12 US disclosed
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230287017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230192636-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230192739-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230200212-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230192665-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230134398-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-05-04 US disclosed
US-20230134398-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-05-04 US disclosed
US-20220302388-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-09-22 US disclosed
US-20220131088-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-28 US disclosed
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2021-11-16 US disclosed
US-20200270262-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed
US-20190002469-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, NONO KIF11 3705/4885LMNA 4558/4885MAPT 1038/4885
US-20230192636-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG KIF11 2549/4885LMNA 2034/4885MAPT 641/4885
US-20230134398-A1 Organic Electroluminescent Materials and Devices ESRRA, GLRA3, GLRA1 KIF11 3775/4885LMNA 876/4885MAPT 4809/4885
US-20220302388-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES C1R, OXSR1, OXER1 KIF11 3560/4885LMNA 1179/4885MAPT 4154/4885
US-20230200212-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SIRT2, OCIAD1 KIF11 4262/4885LMNA 3616/4885MAPT 2154/4885
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes KCNH2, KCNH3, KCNJ2 KIF11 1817/4885LMNA 979/4885MAPT 2580/4885
US-20230363276-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 KIF11 4239/4885LMNA 983/4885MAPT 758/4885
US-20190002469-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES KCNH2, KCNH3, KCNJ2 KIF11 1817/4885LMNA 979/4885MAPT 2580/4885
US-20230329089-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR1H2, OXER1, NR1H3 KIF11 4122/4885LMNA 337/4885MAPT 4351/4885
US-20220131088-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ODC1, OCIAD1, OCIAD2 KIF11 3213/4885LMNA 851/4885MAPT 1731/4885
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 KIF11 3486/4885LMNA 1428/4885MAPT 966/4885
US-20200270262-A1 Organic Electroluminescent Materials and Devices ESRRA, GLRA3, GLRA1 KIF11 3775/4885LMNA 876/4885MAPT 4809/4885
US-20230192714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 KIF11 3654/4885LMNA 1350/4885MAPT 1568/4885
US-20230192665-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 KIF11 4445/4885LMNA 2573/4885MAPT 1201/4885
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 KIF11 1633/4885LMNA 2681/4885MAPT 429/4885
US-20230192739-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 KIF11 2649/4885LMNA 1819/4885MAPT 951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.