Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619600 | 0.82 | SCN10A (0.42) | NPC1LMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL20599108 | 0.82 | GAK (0.42) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL24187946 | 0.82 | BACE1 (0.37) | MAPTALDH1A1 | |
| SCHEMBL20619615 | 0.81 | SCN10A (0.37) | LMNAMAPTALDH1A1 | |
| SCHEMBL20619501 | 0.81 | NR4A2 (0.41) | HCKNR2C2BTKRAB9ASMN1; SMN2 | |
| SCHEMBL24187976 | 0.80 | LMNA (0.43) | NPC1LMNARAB9ASMN1; SMN2MAPT | |
| SCHEMBL20620052 | 0.79 | ALDH1A1 (0.48) | RAB9AMAPTALDH1A1 | |
| SCHEMBL20619918 | 0.73 | SCN10A (0.41) | RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL20598038 | 0.70 | SCN10A (0.42) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL20619496 | 0.70 | SCN10A (0.42) | RAB9ASMN1; SMN2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006295-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |