Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619600 | 0.87 | SCN10A (0.42) | SCN10APDE4BMAPTLMNATP53 | |
| SCHEMBL24187946 | 0.84 | BACE1 (0.37) | SCN10APDE4BMAPTBACE1ALDH1A1 | |
| SCHEMBL24187976 | 0.84 | LMNA (0.43) | SCN10APDE4BMAPTLMNATP53 | |
| SCHEMBL20620052 | 0.82 | ALDH1A1 (0.48) | MAPTALDH1A1 | |
| SCHEMBL20619503 | 0.81 | HCK (0.38) | MAPTLMNAALDH1A1 | |
| SCHEMBL20619918 | 0.77 | SCN10A (0.41) | SCN10APDE4BMAPTALDH1A1 | |
| SCHEMBL20598038 | 0.74 | SCN10A (0.42) | SCN10AMAPTTP53ALDH1A1 | |
| SCHEMBL20619496 | 0.74 | SCN10A (0.42) | SCN10APDE4BMAPTABL1TP53 | |
| SCHEMBL20597986 | 0.73 | MAPK1 (0.42) | SCN10AMAPTTP53ALDH1A1 | |
| SCHEMBL20619910 | 0.72 | MAPT (0.41) | SCN10AMAPTLMNATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006295-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |