Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | USP7 | Q93009 | 3/20 | 0.43 |
| ▸ | USP47 | Q96K76 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955218 | 0.87 | ALDH1A1 (0.44) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19213270 | 0.85 | CES2 (0.52) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL206197 | 0.85 | TSHR (0.57) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11002006 | 0.85 | LMNA (0.47) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10824597 | 0.84 | TSHR (0.55) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4833152 | 0.84 | ALDH1A1 (0.45) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31441001 | 0.84 | ALDH1A1 (0.45) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1625522 | 0.82 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4734285 | 0.81 | TSHR (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL2211359 | 0.81 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12263165-B2 | Small molecule inhibitors of cancer stem cells and mesenchymal cancer types | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-04-01 | — | — | US | disclosed |
| US-20230346781-A1 | SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS AND MESENCHYMAL CANCER TYPES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230346781-A1 | SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS AND MESENCHYMAL CANCER TYPES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230346781-A1 | SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS AND MESENCHYMAL CANCER TYPES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-02 | — | — | US | disclosed |
| US-11759461-B2 | Small molecule inhibitors of cancer stem cells and mesenchymal cancer types | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-19 | — | — | US | disclosed |
| US-11759461-B2 | Small molecule inhibitors of cancer stem cells and mesenchymal cancer types | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-19 | — | — | US | disclosed |
| US-11759461-B2 | Small molecule inhibitors of cancer stem cells and mesenchymal cancer types | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-19 | — | — | US | disclosed |
| US-20210196713-A1 | SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS AND MESENCHYMAL CANCER TYPES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-07-01 | — | — | US | disclosed |
| US-20210196713-A1 | SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS AND MESENCHYMAL CANCER TYPES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-07-01 | — | — | US | disclosed |
| WO-2013050527-A1 | QUINAZOLINE DERIVATIVES AS PDE10A ENZYME INHIBITORS | H. LUNDBECK A/S (DK) | 2013-04-11 | — | — | WO | disclosed |
| US-5663119-A | FOR USE IN AGRICULTURE | RHONE-POULENC AGROCHIMIE (FR) | 1997-09-02 | — | — | US | disclosed |
| US-5523280-A | TREATING PLANT DISEASES | RHONE-POULENC AGROCHIMIE (FR) | 1996-06-04 | — | — | US | disclosed |
| WO-1994002145-A2 | 2-ARYL-4-QUINOLONES AS ANTITUMOR COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 1994-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210196713-A1 | SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS AND MESENCHYMAL CANCER TYPES | VIM, BRCA1, CDH1 | KMT2A 1251/4885MEN1 1951/4885NPC1 4007/4885 |
| US-12263165-B2 | Small molecule inhibitors of cancer stem cells and mesenchymal cancer types | VIM, CDH1, BRCA1 | KMT2A 1156/4885MEN1 1774/4885NPC1 3998/4885 |
| US-20230346781-A1 | SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS AND MESENCHYMAL CANCER TYPES | VIM, CDH1, BRCA1 | KMT2A 1156/4885MEN1 1774/4885NPC1 3998/4885 |
| US-11759461-B2 | Small molecule inhibitors of cancer stem cells and mesenchymal cancer types | VIM, BRCA1, CDH1 | KMT2A 1251/4885MEN1 1951/4885NPC1 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.