Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 2/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9999268 | 0.92 | TSHR (0.63) | LTA4HTSHRHSD17B10ACHEOPRK1 | |
| SCHEMBL6567560 | 0.83 | OPRK1 (0.60) | OPRK1 | |
| SCHEMBL16755611 | 0.81 | LTA4H (0.69) | LTA4HFFAR1TSHRSRD5A2FFAR4 | |
| Water SCHEMBL8160723 | 0.81 | OPRK1 (0.58) | OPRK1 | |
| SCHEMBL1082295 | 0.81 | LTA4H (0.69) | LTA4HFFAR1TSHRSRD5A2FFAR4 | |
| SCHEMBL9999325 | 0.80 | OPRK1 (0.49) | FFAR1TSHROPRK1MMP12MMP13 | |
| Hydrochloric Acid SCHEMBL8692144 | 0.80 | LTA4H (0.67) | LTA4HFFAR1TSHRSRD5A2FFAR4 | |
| SCHEMBL2062580 | 0.79 | LTA4H (0.51) | LTA4HFFAR1ACHENPY5RSRD5A2 | |
| SCHEMBL6567515 | 0.79 | AOC3 (0.58) | — | |
| Diphenylether SCHEMBL28328603 | 0.79 | TSHR (0.50) | LTA4HFFAR1TSHRHSD17B10MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076333-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2011-12-13 | — | — | US | claimed |
| EP-2888224-B1 | PHENOXY ALKYL DIETHANOLAMINE AND DIISOPROPANOLAMINE COMPOUNDS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2017-11-15 | — | — | EP | disclosed |
| US-8148578-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-8148578-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-8148578-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-8076333-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-20110301244-A1 | FAST ACTING NARATRIPTAN COMPOSITION | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301244-A1 | FAST ACTING NARATRIPTAN COMPOSITION | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301244-A1 | FAST ACTING NARATRIPTAN COMPOSITION | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20090253702-A1 | FAST ACTING NARATRIPTAN COMPOSITION | EMISPHERE TECHNOLOGIES INC. (US) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253702-A1 | FAST ACTING NARATRIPTAN COMPOSITION | HTR1D, HTR3E, HPD | LTA4H 194/4885FFAR1 2274/4885TSHR 3829/4885 |
| US-20110301244-A1 | FAST ACTING NARATRIPTAN COMPOSITION | HTR1D, HTR3E, HPD | LTA4H 194/4885FFAR1 2274/4885TSHR 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.