Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062575 | 0.92 | LTA4H (0.56) | TSHRHSD17B10OPRK1ACHELTA4H | |
| SCHEMBL9999446 | 0.83 | DRD2 (0.55) | TSHRHSD17B10DRD2DRD3OPRM1 | |
| SCHEMBL9999395 | 0.80 | TSHR (0.53) | TSHRHSD17B10BCHE | |
| SCHEMBL15499229 | 0.78 | DRD2 (0.53) | TSHRHSD17B10DRD2DRD3OPRM1 | |
| SCHEMBL552965 | 0.77 | DRD3 (0.71) | BCHEDRD2DRD3OPRM1OPRD1 | |
| SCHEMBL6567560 | 0.77 | OPRK1 (0.60) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL6567515 | 0.76 | AOC3 (0.58) | — | |
| Water SCHEMBL8160723 | 0.75 | OPRK1 (0.58) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL427538 | 0.75 | LTA4H (0.59) | TSHRLTA4H | |
| SCHEMBL16755611 | 0.75 | LTA4H (0.69) | TSHRLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148578-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-8076333-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-20110301244-A1 | FAST ACTING NARATRIPTAN COMPOSITION | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20090253702-A1 | FAST ACTING NARATRIPTAN COMPOSITION | EMISPHERE TECHNOLOGIES INC. (US) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253702-A1 | FAST ACTING NARATRIPTAN COMPOSITION | HTR1D, HTR3E, HPD | TSHR 3829/4885HSD17B10 797/4885BCHE 1711/4885 |
| US-20110301244-A1 | FAST ACTING NARATRIPTAN COMPOSITION | HTR1D, HTR3E, HPD | TSHR 3829/4885HSD17B10 797/4885BCHE 1711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.