SCHEMBL20626652

SCHEMBL20626652

O=C(O)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LIPE Q05469 16/20 0.67
BCHE P06276 1/20 0.65
LMNA P02545 1/20 0.65
RAB9A P51151 1/20 0.64
MAPT P10636 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5647580 0.87 LIPE (0.65) LIPEBCHELMNARAB9AMAPT
SCHEMBL11194284 0.86 RAB9A (0.66) LIPEBCHELMNARAB9AMAPT
SCHEMBL11351938 0.86 MAPT (0.69) LIPEBCHELMNARAB9AMAPT
SCHEMBL4327207 0.85 LMNA (0.73) LIPEBCHELMNARAB9AMAPT
SCHEMBL9862017 0.84 LMNA (0.51) LIPEBCHELMNARAB9AMAPT
SCHEMBL8581981 0.83 LMNA (0.63) LIPEBCHELMNARAB9A
SCHEMBL29009446 0.83 LMNA (0.62) LIPEBCHELMNARAB9AMAPT
SCHEMBL10944778 0.83 LMNA (0.62) LIPEBCHELMNARAB9AMAPT
SCHEMBL3200398 0.82 LIPE (0.62) LIPEBCHELMNARAB9AMAPT
SCHEMBL8413343 0.82 SMN1; SMN2 (0.62) LIPEBCHELMNARAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11299745-B1 Herbicide resistance genes DOW AGROSCIENCES LLC (US) 2022-04-12 US disclosed
US-11149283-B2 Herbicide resistance genes DOW AGROSCIENCES LLC (US) 2021-10-19 US disclosed
US-20210147867-A1 NOVEL HERBICIDE RESISTANCE GENES DOW AGROSCIENCES LLC 2021-05-20 US disclosed
US-10174337-B2 Herbicide resistance genes DOW AGROSCIENCES LLC (US) 2019-01-08 US disclosed