Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | LIPE | Q05469 | 11/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20626652 | 0.84 | LIPE (0.67) | LMNARAB9ALIPEBCHEMAPT | |
| SCHEMBL10435427 | 0.84 | RAB9A (0.50) | LMNARAB9AMRGPRX4LIPEKMT2A | |
| SCHEMBL6634752 | 0.84 | KMT2A (0.57) | LMNARAB9AMRGPRX4LIPEKMT2A | |
| SCHEMBL27906089 | 0.84 | LMNA (0.54) | LMNARAB9AMRGPRX4LIPEKMT2A | |
| SCHEMBL27653581 | 0.82 | LMNA (0.56) | LMNARAB9AMRGPRX4LIPEKMT2A | |
| SCHEMBL16712287 | 0.82 | SMN1; SMN2 (0.42) | LMNARAB9ALIPEKMT2AMAPT | |
| SCHEMBL217941 | 0.80 | TSHR (0.50) | LMNARAB9AMRGPRX4LIPEKMT2A | |
| SCHEMBL31387018 | 0.80 | KMT2A (0.47) | LMNARAB9AMRGPRX4LIPEKMT2A | |
| SCHEMBL20808089 | 0.79 | MRGPRX4 (0.56) | LMNARAB9AMRGPRX4LIPEKMT2A | |
| SCHEMBL60180 | 0.79 | NPC1 (0.59) | LMNARAB9AMRGPRX4LIPEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034917-B1 | 2-SUBSTITUTED-5-TRIFLUOROMETHYLPYRIDINES AND A PROCESS FOR PRODUCING THE SAME | ISHIHARA SANGYO KAISHA LTD. (JP) | 1984-08-08 | — | — | EP | claimed |
| EP-0428483-A1 | Synergistic agent and method of selective weed control | CIBA-GEIGY AG (CH) | 1991-05-22 | — | — | EP | disclosed |