Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | FOS | P01100 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057775 | 0.93 | PLA2G4A (0.43) | PLA2G4AFOSJUNALDH1A1MAPT | |
| SCHEMBL15057589 | 0.90 | PLA2G4A (0.42) | PLA2G4AFOSJUNALDH1A1MAPT | |
| SCHEMBL15057237 | 0.88 | RORC (0.42) | PLA2G4AFOSJUNALDH1A1MAPT | |
| SCHEMBL15057343 | 0.85 | ALDH1A1 (0.41) | PLA2G4AFOSJUNALDH1A1MAPT | |
| SCHEMBL15076168 | 0.84 | PTGER1 (0.44) | PLA2G4AALDH1A1MAPTPKMTSHR | |
| SCHEMBL15076165 | 0.84 | PTGER1 (0.53) | PTGER1 | |
| SCHEMBL20628878 | 0.84 | PTGER1 (0.40) | PLA2G4AALDH1A1MAPTPKMTSHR | |
| SCHEMBL15057507 | 0.84 | EPHX2 (0.38) | FOSJUNALDH1A1MAPTPKM | |
| SCHEMBL15076249 | 0.84 | PTGER1 (0.41) | PLA2G4AALDH1A1MAPTPKMTSHR | |
| SCHEMBL20629090 | 0.83 | FOS (0.37) | PLA2G4AFOSJUNALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |