Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 2/20 | 0.37 |
| ▸ | JUN | P05412 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 11/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20628806 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTPKMTSHRHTT | |
| SCHEMBL20628871 | 0.85 | FOS (0.37) | FOSJUNALDH1A1MAPTPKM | |
| SCHEMBL15057589 | 0.84 | PLA2G4A (0.42) | FOSJUNALDH1A1MAPTPKM | |
| SCHEMBL20629004 | 0.83 | PLA2G4A (0.42) | FOSJUNALDH1A1MAPTPKM | |
| SCHEMBL15057921 | 0.83 | FOS (0.38) | FOSJUNALDH1A1MAPTPKM | |
| SCHEMBL15057775 | 0.81 | PLA2G4A (0.43) | FOSJUNALDH1A1MAPTPKM | |
| SCHEMBL15057507 | 0.80 | EPHX2 (0.38) | FOSJUNALDH1A1MAPTPKM | |
| SCHEMBL15057237 | 0.78 | RORC (0.42) | FOSJUNALDH1A1MAPTPKM | |
| SCHEMBL15057366 | 0.78 | EPHX2 (0.41) | ALDH1A1MAPTPKMTSHRHTT | |
| SCHEMBL20628878 | 0.77 | PTGER1 (0.40) | ALDH1A1MAPTPKMTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |