Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 2/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20630799 | 0.94 | POLH (0.66) | POLHKDM4ERECQLMEN1MAPT | |
| SCHEMBL20631332 | 0.93 | POLH (0.62) | POLHKDM4ERECQLMEN1MAPT | |
| SCHEMBL20631304 | 0.91 | POLH (0.62) | POLHKDM4ERECQLMEN1MAPT | |
| SCHEMBL20630770 | 0.90 | POLH (0.67) | POLHKDM4ERECQLMEN1MAPT | |
| SCHEMBL20630208 | 0.88 | POLH (0.65) | POLHKDM4ERECQLMEN1MAPT | |
| SCHEMBL20630949 | 0.86 | POLH (0.68) | POLHKDM4ERECQLMEN1MAPT | |
| SCHEMBL24497194 | 0.83 | POLH (0.72) | POLHKDM4ERECQLMEN1MAPT | |
| SCHEMBL20631318 | 0.82 | POLH (0.67) | POLHKDM4ERECQLMEN1MAPT | |
| SCHEMBL20630205 | 0.82 | POLH (0.56) | POLHKDM4ERECQLMEN1MAPT | |
| SCHEMBL20630753 | 0.81 | POLH (0.64) | POLHKDM4ERECQLMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118186-A1 | SENOTHERAPEUTIC COMPOUND | BIONEXA S.R.L. (IT) | 2022-06-09 | — | — | WO | disclosed |
| US-20200323814-A1 | MEDICAL COMPOUND | VERA SALUS RICERCA S.R.L. (IT) | 2020-10-15 | — | — | US | disclosed |
| WO-2019008537-A9 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2020-02-20 | — | — | WO | disclosed |
| WO-2019008537-A1 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2019-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200323814-A1 | MEDICAL COMPOUND | MTNR1B, CBR1, MTNR1A | POLH 3942/4885KDM4E 3339/4885RECQL 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.