Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20633094 | 0.98 | PIK3CD (0.33) | KDM1ANPC1PKMRAB9APIK3CD | |
| SCHEMBL20632804 | 0.94 | KDM1A (0.38) | KDM1A | |
| SCHEMBL20632389 | 0.84 | SMN1; SMN2 (0.35) | NPC1PKMRAB9A | |
| SCHEMBL20633005 | 0.83 | LMNA (0.38) | KDM1ANPC1RAB9A | |
| SCHEMBL20631406 | 0.83 | PHGDH (0.38) | — | |
| SCHEMBL20632995 | 0.83 | GRIN1 (0.31) | GRIN1GRIN2B | |
| SCHEMBL20632245 | 0.83 | LRRK2 (0.33) | KDM1A | |
| SCHEMBL20632313 | 0.82 | PHGDH (0.33) | NPC1RAB9A | |
| SCHEMBL20632664 | 0.82 | KDM1A (0.34) | KDM1AGRIN1GRIN2B | |
| SCHEMBL20632258 | 0.81 | PIK3CA (0.37) | NPC1PKMRAB9APIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997029-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2019-01-09 | — | — | EP | disclosed |