Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XBP1 | P17861 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631655 | 0.88 | CHRNB2 (0.32) | XBP1NPC1TNFNPSR1NOD2 | |
| SCHEMBL20632508 | 0.87 | NPSR1 (0.35) | XBP1NPC1TNFNPSR1NOD2 | |
| SCHEMBL20632322 | 0.86 | ALOX15 (0.41) | NPSR1ALDH1A1 | |
| SCHEMBL20632360 | 0.85 | USP7 (0.33) | ALDH1A1 | |
| SCHEMBL20632945 | 0.85 | NPSR1 (0.32) | XBP1NPC1TNFNPSR1NOD2 | |
| SCHEMBL20631544 | 0.83 | WNT3A (0.37) | RAB9A | |
| SCHEMBL20633142 | 0.80 | ALOX12 (0.35) | HTT | |
| SCHEMBL20632456 | 0.79 | SYK (0.36) | XBP1NPC1TNFNPSR1NOD2 | |
| SCHEMBL20632320 | 0.79 | NPC1 (0.31) | NPC1NPSR1RAB9A | |
| SCHEMBL20632436 | 0.79 | ALOX15 (0.37) | NPC1NPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997029-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2019-01-09 | — | — | EP | disclosed |