SCHEMBL206480

SCHEMBL206480

O=[N+]([O-])c1ccc(N=C=S)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
NOS1 P29475 4/20 0.48
P2RY6 Q15077 1/20 0.47
MIF P14174 1/20 0.46
ALDH1A1 P00352 5/20 0.45
ACHE P22303 1/20 0.45
HSD17B10 Q99714 1/20 0.45
APP P05067 1/20 0.44
NOS3 P29474 2/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
CASP3 P42574 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitroscanate SCHEMBL381451 0.91 HSPB1 (0.56) PLAUCA1CA2ALDH1A1HSD17B10
Amoscanate SCHEMBL159478 0.89 HPGD (0.56) PLAUCA1CA2NOS1ALDH1A1
SCHEMBL10622842 0.89 MAPT (0.54) PLAUCA1CA2NOS1P2RY6
SCHEMBL6894771 0.85 ALDH1A1 (0.50) MIFALDH1A1LMNASMN1; SMN2MAPT
Nitrobenzene SCHEMBL27619235 0.83 ALDH1A1 (0.52) PLAUCA1CA2NOS1P2RY6
SCHEMBL508121 0.83 PLAU (0.53) PLAUCA1CA2NOS1ALDH1A1
SCHEMBL11720520 0.82 MEN1 (0.40) PLAUCA1CA2NOS1ALDH1A1
SCHEMBL62027 0.81 PLAU (0.52) PLAUCA1CA2NOS1ALDH1A1
SCHEMBL11710183 0.79 NPC1 (0.40) CA1CA2ALDH1A1APPLMNA
SCHEMBL15630319 0.79 P2RY6 (0.47) PLAUCA1CA2NOS1P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12402638-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-09-02 US claimed
CN-115515998-B Synthesis of polyurethanes by chain growth copolymerization 伊夫·雅努 2025-06-24 CN claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
US-20250100980-A1 NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) 2025-03-27 US claimed
US-12232516-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-02-25 US claimed
US-12193465-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-01-14 US claimed
CN-119080660-A Thiosemicarbazide menthyl formate compound, preparation method and application thereof 南京林业大学 2024-12-06 CN claimed
CN-115894909-B Polyethylenimine nitrophenyl thiourea probe, preparation method and application thereof in recognition of anions 新疆大学 2024-06-04 CN claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
WO-2010065329-A2 NANOPARTICLES FOR CANCER TREATMENT THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-06-10 WO claimed
US-7732534-B2 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2010-06-08 US claimed
WO-2009066981-A1 IMMOBILIZED NITRATE IONOPHORE MIMOS BERHAD (MY) 2009-05-28 WO claimed
US-20080051552-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION 2008-02-28 US claimed
US-20080051519-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2008-02-28 US claimed
CN-100351229-C 5,11,17,23-tetra (p-tert-butyl)-25,27-dilp-nitrobenzenethioureido-(1'R,2'R)-1',2'-diphenylethylamino-carbonyl methoxyl J-26, 28-dihydroxyl cup [4} arene UNIV WUHAN (CN) 2007-11-28 CN claimed
US-20060241178-A1 Compositions and methods for treating lung cancer IMMUNEGUARD LLC (US) 2006-10-26 US claimed
CN-1810784-A 5,11,17,23-tetra (p-tert-butyl)-25,27-dilp-nitrobenzenethioureido-(1'R,2'R)-1',2'-diphenylethylamino-carbonyl methoxyl J-26, 28-dihydroxyl cup [4} arene UNIV WUHAN (CN) 2006-08-02 CN claimed
WO-2004060365-A1 COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER AMERICAN HEALTH FOUNDATION (US) 2004-07-22 WO claimed
EP-0928311-B1 SHAPING OBJECT WITH REACTIVE FUNCTIONS BIOTECHNOLOG FORSCHUNG GMBH (DE) 2003-04-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250100980-A1 NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF LTB4R2, LTB4R, CYSLTR2 PLAU 473/4885CA1 4790/4885CA2 4126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.