SCHEMBL20650282

SCHEMBL20650282

CC(C)(C)c1ccccc1N(I)c1cccc2c1sc1ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.37
PARP14 Q460N5 1/20 0.35
ALOX5 P09917 1/20 0.35
APEX1 P27695 1/20 0.34
MAPT P10636 3/20 0.34
KIF11 P52732 1/20 0.33
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
RAB9A P51151 3/20 0.31
ALDH1A1 P00352 3/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
ATM Q13315 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CA2 P00918 1/20 0.31
TSHR P16473 2/20 0.30
PTPN7 P35236 1/20 0.30
DUSP3 P51452 1/20 0.30
PTPN12 Q05209 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650237 0.90 KIF11 (0.34) KIF11ALDH1A1CA2TSHRTDP1
SCHEMBL20650374 0.86 GABRA1 (0.36) KIF11
SCHEMBL23967665 0.85 HDAC3 (0.33) KIF11
SCHEMBL20172868 0.84 GPR3 (0.38) GPR3PARP14ALOX5APEX1MAPT
SCHEMBL20650823 0.82 SIGMAR1 (0.30) KIF11
SCHEMBL20649784 0.82 NR1I2 (0.30) KIF11LMNA
SCHEMBL20650281 0.82 GPR3 (0.39) GPR3PARP14ALOX5MAPTRAB9A
SCHEMBL20649761 0.82 KIF11 (0.31) KIF11
SCHEMBL20650288 0.80 GPR3 (0.41) GPR3PARP14ALOX5MAPTRAB9A
SCHEMBL23967805 0.80 GABRA1 (0.36) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed