Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352988 | 0.83 | CSNK2A1 (0.59) | CSNK2A1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28674119 | 0.81 | KDM4E (0.50) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL23447635 | 0.79 | NR4A2 (0.49) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL467550 | 0.78 | CSNK2A1 (0.68) | CSNK2A1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31627797 | 0.78 | CSNK2A1 (0.68) | CSNK2A1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| Boric Acid SCHEMBL27962488 | 0.78 | CSNK2A1 (0.57) | CSNK2A1ALDH1A1MEN1KMT2AMCL1 | |
| SCHEMBL9939276 | 0.78 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2ACA1 | |
| SCHEMBL9938748 | 0.78 | KEAP1 (0.50) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL7476031 | 0.76 | CSNK2A1 (0.39) | CSNK2A1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6234004 | 0.76 | CSNK2A1 (0.65) | CSNK2A1ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400222-B1 | ZWITTERIONIC PROPARGYL-LINKED ANTIFOLATES USEFUL FOR TREATING BACTERIAL INFECTIONS | UNIV CONNECTICUT (US) | 2021-07-14 | — | — | EP | disclosed |
| US-10870625-B2 | Zwitterionic propargyl-linked antifolates useful for treating bacterial infections | UNIVERSITY OF CONNECTICUT (US) | 2020-12-22 | — | — | US | disclosed |
| US-20190002413-A1 | ZWITTERIONIC PROPARGYL-LINKED ANTIFOLATES USEFUL FOR TREATING BACTERIAL INFECTIONS | THE UNIVERSITY OF CONNECTICUT (US) | 2019-01-03 | — | — | US | disclosed |
| EP-3400222-A1 | ZWITTERIONIC PROPARGYL-LINKED ANTIFOLATES USEFUL FOR TREATING BACTERIAL INFECTIONS | The University of Connecticut (US) | 2018-11-14 | — | — | EP | disclosed |
| EP-2699569-B1 | AMINOPYRIMIDINE KINASE INHIBITORS | JASCO PHARMACEUTICALS LLC (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2699569-B1 | AMINOPYRIMIDINE KINASE INHIBITORS | JASCO PHARMACEUTICALS LLC (US) | 2017-08-30 | — | — | EP | disclosed |
| WO-2017120575-A1 | ZWITTERIONIC PROPARGYL-LINKED ANTIFOLATES USEFUL FOR TREATING BACTERIAL INFECTIONS | THE UNIVERSITY OF CONNECTICUT (US) | 2017-07-13 | — | — | WO | disclosed |
| US-8901145-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901145-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901145-B2 | Aminopyrimidine kinase inhibitors | Jasco Pharmaceuticals, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| EP-2699569-A2 | AMINOPYRIMIDINE KINASE INHIBITORS | Jasco Pharmaceuticals LLC (US) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012145617-A9 | AMINOPYRIMIDINE KINASE INHIBITORS | Jasco Pharmaceuticals, LLC (US) | 2014-02-20 | — | — | WO | disclosed |
| WO-2012145617-A2 | AMINOPYRIMIDINE KINASE INHIBITORS | Jasco Pharmaceuticals, LLC (US) | 2012-10-26 | — | — | WO | disclosed |
| WO-2012145617-A2 | AMINOPYRIMIDINE KINASE INHIBITORS | Jasco Pharmaceuticals, LLC (US) | 2012-10-26 | — | — | WO | disclosed |
| US-20120270892-A1 | Aminopyrimidine Kinase Inhibitors | Jasco Pharmaceuticals, LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120270892-A1 | Aminopyrimidine Kinase Inhibitors | Jasco Pharmaceuticals, LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120270892-A1 | Aminopyrimidine Kinase Inhibitors | Jasco Pharmaceuticals, LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-8148519-B2 | Porphyrin-based photosensitizer dyes for dye-sensitized solar cells | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2012-04-03 | — | — | US | disclosed |
| US-20100125136-A1 | PORPHYRIN-BASED PHOTOSENSITIZER DYES FOR DYE-SENSITIZED SOLAR CELLS | DC SOLAR CORP. A TAIWAN CORPORATION (TW) | 2010-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002413-A1 | ZWITTERIONIC PROPARGYL-LINKED ANTIFOLATES USEFUL FOR TREATING BACTERIAL INFECTIONS | DHFR, FOLR1, FOLR2 | CSNK2A1 4003/4885ALDH1A1 1387/4885SMN1; SMN2 3892/4885 |
| US-10870625-B2 | Zwitterionic propargyl-linked antifolates useful for treating bacterial infections | DHFR, FOLR1, FOLR2 | CSNK2A1 4003/4885ALDH1A1 1387/4885SMN1; SMN2 3892/4885 |
| US-20120270892-A1 | Aminopyrimidine Kinase Inhibitors | PIM1, PIM2, PIM3 | CSNK2A1 10/4885ALDH1A1 3305/4885SMN1; SMN2 3597/4885 |
| US-20100125136-A1 | PORPHYRIN-BASED PHOTOSENSITIZER DYES FOR DYE-SENSITIZED SOLAR CELLS | DNAH12, SLC39A3, CRY1 | CSNK2A1 1334/4885ALDH1A1 2030/4885SMN1; SMN2 4451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.