Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891032 | 0.87 | ALDH1A3 (0.41) | ALDH1A1POLBKMT2AGAAPARP10 | |
| SCHEMBL2881391 | 0.80 | TDP1 (0.52) | TDP1MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL38655995 | 0.80 | TDP1 (0.52) | TDP1MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL5563 | 0.80 | PARP10 (0.54) | TDP1MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL9096551 | 0.80 | TDP1 (0.50) | TDP1MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL18948912 | 0.78 | TDP1 (0.50) | TDP1MAPK1ALDH1A1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL4963793 | 0.78 | TDP1 (0.54) | TDP1MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL3821124 | 0.77 | TDP1 (0.44) | TDP1MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL5635955 | 0.76 | TDP1 (0.48) | TDP1MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL8889526 | 0.76 | TDP1 (0.54) | TDP1MAPK1ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731932-B2 | Silicon-containing compositions and their methods of use | ADITYA BIRLA CHEMICALS (USA), INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20220356145-A1 | SILICON-CONTAINING COMPOSITIONS AND THEIR METHODS OF USE | ADITYA BIRLA CHEMICALS (USA) LLC | 2022-11-10 | — | — | US | disclosed |
| US-10919839-B2 | Silicon-containing compositions and their methods of use | ADITYA BIRLA CHEMICALS (USA) LLC (US) | 2021-02-16 | — | — | US | disclosed |
| US-20190016870-A1 | SILICON-CONTAINING COMPOSITIONS AND THEIR METHODS OF USE | ADITYA BIRLA CHEMICALS (USA), INC. | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919839-B2 | Silicon-containing compositions and their methods of use | SRM, REV1, RER1 | TDP1 1831/4885MAPK1 4754/4885ALDH1A1 3388/4885 |
| US-20220356145-A1 | SILICON-CONTAINING COMPOSITIONS AND THEIR METHODS OF USE | SRM, REV1, RER1 | TDP1 1831/4885MAPK1 4754/4885ALDH1A1 3388/4885 |
| US-11731932-B2 | Silicon-containing compositions and their methods of use | SRM, REV1, RER1 | TDP1 1831/4885MAPK1 4754/4885ALDH1A1 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.