SCHEMBL471725

SCHEMBL471725

NCCN1CCN(CCN)C1=O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.41
DRD3 P35462 8/20 0.34
KCNH2 Q12809 3/20 0.34
DRD2 P14416 7/20 0.32
POLB P06746 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21681741 0.90 ALOX15 (0.38) ALOX15DRD3DRD2
SCHEMBL10851707 0.89 PER2 (0.33) ALOX15DRD3KCNH2
SCHEMBL10868666 0.89 ALOX15 (0.33) ALOX15DRD3KCNH2POLBCYP2D6
SCHEMBL10849278 0.89 L3MBTL1 (0.37) ALOX15DRD3KCNH2POLBKMT2A
SCHEMBL21711072 0.87 ACE2 (0.43) ALOX15KMT2A
SCHEMBL1447298 0.85 ALOX15 (0.35) ALOX15DRD3DRD2
SCHEMBL10850120 0.85 MEN1 (0.39) KMT2A
SCHEMBL9190064 0.84 KEAP1 (0.38) ALOX15DRD3KCNH2DRD2CYP2D6
SCHEMBL20656064 0.83 ACE2 (0.50) ALOX15CYP2C19KMT2A
SCHEMBL10854804 0.83 GBA1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11135544-B2 Acidic gas absorbent, acidic gas removal method and acidic gas removal apparatus KABUSHIKI KAISHA TOSHIBA (JP) 2021-10-05 US claimed
EP-3414223-B1 PROCESS TO CONVERT CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES NOURYON CHEMICALS INT BV (NL) 2021-04-07 EP claimed
US-20200047110-A1 ACIDIC GAS ABSORBENT, ACIDIC GAS REMOVAL METHOD AND ACIDIC GAS REMOVAL APPARATUS KABUSHIKI KAISHA TOSHIBA (JP) 2020-02-13 US claimed
US-20190039994-A1 PROCESS TO CONVERT CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2019-02-07 US claimed
EP-2649112-B1 PRODUCTION OF AN ARTICLE BY SELECTIVE FUSION OF POLYMER POWDER LAYERS RHODIA OPERATIONS (FR) 2018-03-21 EP claimed
EP-2734507-B1 PROCESS FOR THE SYNTHESIS OF N-SUBSTITUTED CYCLIC ALKYLENE UREAS ALLNEX IP S À R L (LU) 2017-05-31 EP claimed
US-9321192-B2 Production of an article by selective fusion of polymer powder layers RHODIA OPERATIONS (FR) 2016-04-26 US claimed
US-20140179931-A1 Process for the Synthesis of N-Substituted Cyclic Alkylene Ureas ALLNEX USA INC. (US) 2014-06-26 US claimed
US-20130307196-A1 PRODUCTION OF AN ARTICLE BY SELECTIVE FUSION OF POLYMER POWDER LAYERS RHODIA OPERATIONS (FR) 2013-11-21 US claimed
US-11697735-B2 Solid oleaginous compositions TOTAL MARKETING SERVICES (FR) 2023-07-11 US disclosed
US-11697735-B2 Solid oleaginous compositions TOTAL MARKETING SERVICES (FR) 2023-07-11 US disclosed
US-11365317-B2 Solid binders TOTAL MARKETING SERVICES (FR) 2022-06-21 US disclosed
EP-3612616-B1 SOLID BITUMEN AT AMBIENT TEMPERATURE TOTAL MARKETING SERVICES (FR) 2022-06-01 EP disclosed
US-11339116-B2 Reactive separation process to convert cyclic alkylene ureas into their corresponding alkylene amines NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-05-24 US disclosed
EP-0687288-A1 MANNICH CONDENSATION PRODUCTS OF POLY(OXYALKYLENE) HYDROXYAROMATIC ESTERS AND FUEL COMPOSITIONS CONTAINING THE SAME CHEVRON CHEMICAL COMPANY (US) 1995-12-20 EP disclosed
WO-1995029971-A1 MANNICH CONDENSATION PRODUCTS OF POLY(OXYALKYLENE) HYDROXYAROMATIC CARBAMATES AND FUEL COMPOSITIONS CONTAINING THE SAME CHEVRON CHEMICAL COMPANY (US) 1995-11-09 WO disclosed
WO-1995018197-A1 MANNICH CONDENSATION PRODUCTS OF POLY(OXYALKYLENE) HYDROXYAROMATIC ESTERS AND FUEL COMPOSITIONS CONTAINING THE SAME CHEVRON CHEMICAL COMPANY (US) 1995-07-06 WO disclosed
EP-0658573-A2 Mannich condensation products of polyalkylene hydroxyaromatic esters and fuel compositions containing the same CHEVRON CHEMICAL COMPANY (US) 1995-06-21 EP disclosed
US-5413614-A Antideposit CHEVRON CHEMICAL COMPANY (US) 1995-05-09 US disclosed
US-5399178-A Antideposit agents CHEVRON CHEMICAL COMPANY (US) 1995-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190039994-A1 PROCESS TO CONVERT CYCLIC ALKYLENE UREAS INTO THEIR CORRESPONDING ALKYLENE AMINES UBE2I, NAT10, UBE2M ALOX15 2964/4885DRD3 2159/4885KCNH2 1358/4885
US-11339116-B2 Reactive separation process to convert cyclic alkylene ureas into their corresponding alkylene amines UTP20, CGAS, UMPS ALOX15 2542/4885DRD3 1979/4885KCNH2 1338/4885
US-20140179931-A1 Process for the Synthesis of N-Substituted Cyclic Alkylene Ureas CA4, CA2, CDYL ALOX15 4231/4885DRD3 1747/4885KCNH2 86/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.