SCHEMBL20657235

SCHEMBL20657235

CC=CC(=O)NCCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 4/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
PLA2G2A P14555 1/20 0.39
APEX1 P27695 1/20 0.39
ALDH1A1 P00352 2/20 0.37
POLB P06746 2/20 0.37
KDM4E B2RXH2 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
FAAH O00519 2/20 0.37
CNR1 P21554 2/20 0.37
CNR2 P34972 2/20 0.37
ADRA1A P35348 1/20 0.36
PPARG P37231 1/20 0.36
PPARD Q03181 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20657261 0.88 KMT2A (0.49) APEX1ALDH1A1POLBKDM4EKMT2A
SCHEMBL28459307 0.88 KMT2A (0.49) APEX1ALDH1A1POLBKDM4EKMT2A
SCHEMBL20657255 0.86 ADRA1A (0.55) PLA2G2AAPEX1ALDH1A1POLBKDM4E
SCHEMBL9829252 0.84 ADRA1A (0.58) PLA2G2AAPEX1POLBADRA1APRMT1
SCHEMBL28416594 0.84 ADRA1A (0.58) PLA2G2AAPEX1POLBADRA1APRMT1
SCHEMBL22200049 0.84 ADRA1A (0.58) PLA2G2AAPEX1POLBADRA1APRMT1
SCHEMBL9829255 0.84 ADRA1A (0.58) PLA2G2AAPEX1POLBADRA1APRMT1
SCHEMBL14642043 0.84 SMN1; SMN2 (0.46) SMN1; SMN2APEX1ALDH1A1KMT2AMAPT
SCHEMBL22187119 0.84 SMN1; SMN2 (0.46) SMN1; SMN2APEX1ALDH1A1KMT2AMAPT
SCHEMBL25146405 0.81 ECE1 (0.41) ECE1PLA2G2AALDH1A1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
US-20230374306-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 US claimed
US-20230357478-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-09 US claimed
WO-2023209569-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
US-20230339149-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US claimed
US-20230339148-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US claimed
US-11618823-B2 High refractive index siloxane insert materials for embedded contact lenses ALCON INC. (CH) 2023-04-04 US claimed
EP-4146461-A1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2023-03-15 EP claimed
US-20210292558-A1 EMBEDDED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2021-09-23 US claimed
US-20210132411-A1 CONTACT LENSES WITH SURFACES HAVING DIFFERENT SOFTNESS ALCON INC. (CH) 2021-05-06 US claimed
US-10962803-B2 Contact lenses with a lubricious coating thereon ALCON INC. (CH) 2021-03-30 US claimed
US-10920099-B2 Poly(meth)acrylamide-based copolymers with carboxyl-terminated pendant chains ALCON INC. (CH) 2021-02-16 US claimed
EP-3746820-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON Alcon Inc. (CH) 2020-12-09 EP claimed
CN-111566517-A Contact lenses having lubricious coating thereon 爱尔康公司 2020-08-21 CN claimed
EP-3655446-A1 POLY(METH)ACRYLAMIDE-BASED COPOLYMERS WITH CARBOXYL-TERMINATED PENDANT CHAINS ALCON INC. (CH) 2020-05-27 EP claimed
US-20190235277-A1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC. (CH) 2019-08-01 US claimed
WO-2019016696-A1 POLY(METH)ACRYLAMIDE-BASED COPOLYMERS WITH CARBOXYL-TERMINATED PENDANT CHAINS NOVARTIS AG (CH) 2019-01-24 WO claimed
US-20190023935-A1 POLY(METH)ACRYLAMIDE-BASED COPOLYMERS WITH CARBOXYL-TERMINATED PENDANT CHAINS ALCON INC. (CH) 2019-01-24 US claimed